Home News About Us Contact Contributors Disclaimer Privacy Policy Help FAQ

Home
Search
Quick Search
Advanced
Fulltext
Browse
Collections
Persons
My eDoc
Session History
Login
Name:
Password:
Documentation
Help
Support Wiki
Direct access to
document ID:


          Display Documents



  history
ID: 16922.0, MPI für biophysikalische Chemie / Molekulare Zellbiologie (Prof. Peter Gruss)
Generating neuronal diversity in the retina: one for nearly all
Authors:Marquardt, T.; Gruss, P.
Language:English
Date of Publication (YYYY-MM-DD):2002-01
Title of Journal:Trends in Neurosciences
Volume:25
Issue / Number:1
Start Page:32
End Page:38
Review Status:not specified
Audience:Not Specified
Abstract / Description:Visual perception of our environment essentially depends on the correct assembly of seven principal cell types into the functional architecture of the neuroretina. During retinogenesis these cell types derive from a common population of multipotent retinal progenitor cells (RPCs) residing in the inner layer of the optic cup. In contrast to other well studied regions of the developing CNS, retinal cell diversification is apparently not achieved by spatial prepatterning into distinct progenitor domains, but rather by the sequential production of cell types in a defined histogenetic order. Several lines of evidence suggest that this observation reflects substantial intrinsic changes in the retinogenic potential of RPCs. Recent advances, however, point at the existence of a common molecular framework underlying the retinogenic potential of RPCs throughout retinal neurogenesis.
Comment of the Author/Creator:Date: 2002, JAN
External Publication Status:published
Document Type:Article
Communicated by:N. N.
Affiliations:MPI für biophysikalische Chemie/Abt. Peter Gruss / 160
External Affiliations:Salk Inst Biol Studies, GEL-P,10010 N Torrey Pines Rd, La; Jolla, CA 92037 USA; Salk Inst Biol Studies, La Jolla, CA 92037 USA
Identifiers:URL:http://www.sciencedirect.com/science?_ob=MImg&_ima...
The scope and number of records on eDoc is subject to the collection policies defined by each institute - see "info" button in the collection browse view.