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ID: 28803.0, MPI für Pflanzenzüchtungsforschung / Dept. Molecular Plant Genetics (Heinz Saedler)
Two ancient classes of MIKC-type MADS-box genes are present in the moss Physcomitrella patens
Authors:Henschel, K.; Kofuji, R.; Hasebe, M.; Saedler, H.; Munster, T.; Theissen, G.
Date of Publication (YYYY-MM-DD):2002-06
Title of Journal:Molecular Biology and Evolution
Journal Abbrev.:Mol. Biol. Evol.
Issue / Number:6
Start Page:801
End Page:814
Review Status:Peer-review
Audience:Experts Only
Abstract / Description:Characterization of seven MADS-box genes, termed PPM1-PPM4 and PpMADS1-PIWADS3, from the moss model species Physcomitrella patens is reported. Phylogeny reconstructions and comparison of exon-intron structures revealed that the genes described here represent two different classes of homologous, yet distinct, MIKC-type MADS-box genes, termed MIKCc-type genes-"(c)"stands for "classic"-(PPM1, PPM2, PpMADS/) and MIKC*type genes (PPM3, PPM4, PpMADS2. PpMADS3). The two gene classes deviate from each other in a characteristic way, especially in a sequence stretch termed intervening region, MIKCc-type genes are abundantly present in all land plants which have been investigated in this respect. and give rise to well-known gene types such as floral meristem and organ identity genes. In contrast, L4MB1 from the clubmoss Lycopodium annotintan was identified as the only other MIKC*-Lype gene published so far. Our findings strongly suggest that the most recent common ancestor of mosses and vascular plants contained at least one MIKCc-type and one MIKC*-type gene. Our studies thus reveal an ancient duplication of an MIKC-type gene that occurred before the separation of the lineages that led to extant mosses and vascular plants more than about 450 MYA. The identification of bona fide K-domains in both MIKCc-type and MIKCc-type proteins suggests that the K- domain is more ancient than is suggested by a recent alternative hypothesis. MIKC"-type genes may have escaped identification in ferns and seed plants so far. It seems more likely, however, that they represent a class of genes which has been lost in the lineage which led to extant ferns and seed plants. The high number of P. patens MADS-box genes and the presence of a K-box in the coding region and of some potential binding sites for MADS-domain proteins and other transcription factors in the putative promoter regions of these genes suggest that MADS-box genes in mosses are involved in complex gene regulatory networks similar to those in flowering plants.
Free Keywords:MADS-box gene; Physcomitrella; moss; evolution
Comment of the Author/Creator:Date: 2002, JUN
External Publication Status:published
Document Type:Article
Communicated by:N.N.
Affiliations:MPI für Pflanzenzüchtungsforschung
External Affiliations:Univ Jena, Lehrstuhl Genet, Philosophenweg 12, D-07743 Jena,; Germany; Max Planck Inst Breeding Res, Dept Mol Plant Genet, Cologne, Germany; Kanazawa Univ, Fac Sci, Kanazawa, Ishikawa 920, Japan; Natl Inst Basic Biol, Okazaki, Aichi 444, Japan
Identifiers:ISI:000176211700002 [ID No:1]
ISSN:0737-4038 [ID No:2]
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