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Entries: 1-10  
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Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions
Authors: Thiel, Philipp; Röglin, Lars; Meissner, Nicole; Hennig, Sven; Kohlbacher, Oliver; Ottmann, Christian
Date of Publication (YYYY-MM-DD): 2013-10-04
Title of Journal: Chemical Communication
Volume: 49
Issue / Number: 76
Start Page: 8468
End Page: 8470
Sequence Number of Article: 1
Document Type: Article
ID: 670157.0
Stabilization of Physical RAF/14-3-3 Interaction by Cotylenin A as Treatment Strategy for RAS Mutant Cancers
Authors: Molzan, Manuela; Kasper, Stefan; Röglin, Lars; Skwarczynska, Malgorzata; Sassa, Takeshi; Inoue, Takatsugu; Breitenbuecher, Frank; Ohkanda, Junko; Kato, Nobuo; Schuler, Martin; Ottmann, Christian
Date of Publication (YYYY-MM-DD): 2013-09-20
Title of Journal: ACS Chemical Biology
Volume: 8
Issue / Number: 9
Start Page: 1869
End Page: 1875
Sequence Number of Article: 1
Document Type: Article
ID: 669338.0
Tandem Orthogonal Chemically Induced Dimerization
Authors: Voss, Stephanie; Wu, Yao-Wen
Date of Publication (YYYY-MM-DD): 2013-09-02
Title of Journal: ChemBioChem
Volume: 14
Issue / Number: 13
Start Page: 1525
End Page: 1527
Sequence Number of Article: 1
Document Type: Article
ID: 669036.0
Targeting Gain of Function and Resistance Mutations in Abl and KIT by Hybrid Compound Design
Authors: Richters, André; Ketzer, Julia; Getlik, Matthäus; Grütter, Christian; Schneider, Ralf; Heuckmann, Johannes M.; Heynck, Stefanie; Sos, Martin L.; Gupta, Anu; Unger, Anke; Schultz-Fademrecht, Carsten; Thomas, Roman K.; Bauer, Sebastian; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2013-07-25
Title of Journal: Journal of Medicinal Chemistry
Volume: 56
Issue / Number: 14
Start Page: 5757
End Page: 5772
Sequence Number of Article: 1
Document Type: Article
ID: 669113.0
Preface: Inhibition and stabilization of protein-protein interactions
Authors: Ottmann, Christian; Robinson, John
Date of Publication (YYYY-MM-DD): 2013-07-15
Title of Journal: Bioorganic & Medicinal Chemistry
Volume: 21
Issue / Number: 14
Start Page: 3981
End Page: 3981
Sequence Number of Article: 1
Document Type: Article
ID: 669118.0
Direct targeting of β-catenin: Inhibition of protein-protein interactions for the inactivation of Wnt signaling
Authors: Hahne, Gernot; Grossmann, Tom N.
Date of Publication (YYYY-MM-DD): 2013-07-15
Title of Journal: Bioorganic & Medicinal Chemistry
Volume: 21
Issue / Number: 14
Start Page: 4020
End Page: 4026
Sequence Number of Article: 1
Document Type: Article
ID: 669119.0
Overcoming Compound Fluorescence in the FLiK Screening Assay with Red-Shifted Fluorophores
Authors: Schneider, Ralf; Gohla, Anne; Simard, Jeffrey R.; Yadav, Dharmendra B.; Fang, Zhizhou; Van Otterlo, Willem A. L.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2013-06-05
Title of Journal: Journal of the American Chemical Society
Volume: 135
Issue / Number: 22
Start Page: 8400
End Page: 8408
Sequence Number of Article: 1
Document Type: Article
ID: 668198.0
Interaction of 14-3-3 proteins with the Estrogen Receptor Alpha F domain provides a drug target interface
Authors: De Vries-van Leeuwen, Ingrid J.; Pereira, Daniel da Costa; Flach, Koen D.; Piersma, Sander R.; Haase, Christian; Bier, David; Yalcin, Zeliha; Michalides, Rob; Feenstra, K. Anton; Jiménez, Connie R.; de Greef, Tom F. A.; Brunsveld, Luc; Ottmann, Christian; Zwart, Wilbert; de Boer, Albertus H.
Date of Publication (YYYY-MM-DD): 2013-05-28
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 110
Issue / Number: 22
Start Page: 8894
End Page: 8899
Sequence Number of Article: 1
Document Type: Article
ID: 669243.0
Selective Detection of Allosteric Phosphatase Inhibitors
Authors: Schneider, Ralf; Beumer, Claudia; Simard, Jeffrey R.; Grütter, Christian; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2013-05-08
Title of Journal: Journal of the American Chemical Society
Volume: 135
Issue / Number: 18
Start Page: 6838
End Page: 6841
Sequence Number of Article: 1
Document Type: Article
ID: 667307.0
A Semisynthetic Fusicoccane Stabilizes a Protein-Protein Interaction and Enhances the Expression of K+ Channels at the Cell Surface
Authors: Anders, Carolin; Higuchi, Yusuke; Koschinsky, Kristin; Bartel, Maria; Schumacher, Benjamin; Thiel, Philipp; Nitta, Hajime; Preisig-Müller, Regina; Schlichthörl, Günter; Renigunta, Vijay; Ohkanda, Junko; Daut, Jürgen; Kato, Nobuo; Ottmann, Christian
Date of Publication (YYYY-MM-DD): 2013-04-18
Title of Journal: Chemistry & Biology
Volume: 20
Issue / Number: 4
Start Page: 583
End Page: 593
Sequence Number of Article: 1
Document Type: Article
ID: 658267.0
Entries: 1-10  
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