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Entries: 1-10  
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Targeting Gain of Function and Resistance Mutations in Abl and KIT by Hybrid Compound Design
Authors: Richters, André; Ketzer, Julia; Getlik, Matthäus; Grütter, Christian; Schneider, Ralf; Heuckmann, Johannes M.; Heynck, Stefanie; Sos, Martin L.; Gupta, Anu; Unger, Anke; Schultz-Fademrecht, Carsten; Thomas, Roman K.; Bauer, Sebastian; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2013-07-25
Title of Journal: Journal of Medicinal Chemistry
Volume: 56
Issue / Number: 14
Start Page: 5757
End Page: 5772
Sequence Number of Article: 1
Document Type: Article
ID: 669113.0
Overcoming Compound Fluorescence in the FLiK Screening Assay with Red-Shifted Fluorophores
Authors: Schneider, Ralf; Gohla, Anne; Simard, Jeffrey R.; Yadav, Dharmendra B.; Fang, Zhizhou; Van Otterlo, Willem A. L.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2013-06-05
Title of Journal: Journal of the American Chemical Society
Volume: 135
Issue / Number: 22
Start Page: 8400
End Page: 8408
Sequence Number of Article: 1
Document Type: Article
ID: 668198.0
Selective Detection of Allosteric Phosphatase Inhibitors
Authors: Schneider, Ralf; Beumer, Claudia; Simard, Jeffrey R.; Grütter, Christian; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2013-05-08
Title of Journal: Journal of the American Chemical Society
Volume: 135
Issue / Number: 18
Start Page: 6838
End Page: 6841
Sequence Number of Article: 1
Document Type: Article
ID: 667307.0
Natural-product-derived fragments for fragment-based ligand discovery
Authors: Over, Björn; Wetzel, Stefan; Grütter, Christian; Nakai, Yasushi; Renner, Steffen; Rauh, Daniel; Waldmann, Herbert
Date of Publication (YYYY-MM-DD): 2013-01
Title of Journal: Nature Chemistry
Volume: 5
Issue / Number: 1
Start Page: 21
End Page: 28
Sequence Number of Article: 1
Document Type: Article
ID: 628939.0
A framework for identification of actionable cancer genome dependencies in small cell lung cancer
Authors: Sos, Martin L.; Dietlein, Felix; Peifer, Martin; Schöttle, Jakob; Balke-Want, Hyatt; Müller, Christian; Koker, Mirjam; Richters, André; Heynck, Stefanie; Malchers, Florian; Heuckmann, Johannes M.; Seidel, Danila; Eyers, Patrick A.; Ullrich, Roland T.; Antonchick, Andrey P.; Vintonyak, Viktor V.; Schneider, Peter M.; Ninomiya, Takashi; Waldmann, Herbert; Büttner, Reinhard; Rauh, Daniel; Heukamp, Lukas C.; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2012-10-16
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 109
Issue / Number: 42
Start Page: 17034
End Page: 17039
Sequence Number of Article: 1
Document Type: Article
ID: 628796.0
Fluorophore Labeled Kinase Detects Ligands That Bind within the MAPK Insert of p38α Kinase
Authors: Getlik, Matthäus; Simard, Jeffrey R.; Termathe, Martin; Grütter, Christian; Rabiller, Matthias; Van Otterlo, Willem A. L.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2012-07-02
Title of Journal: PLoS ONE
Volume: 7
Issue / Number: 7
Start Page: e39713-1
End Page: e39713-10
Sequence Number of Article: 1
Document Type: Article
ID: 611213.0
Direct Binding Assay for the Detection of Type IV Allosteric Inhibitors of Abl
Authors: Schneider, Ralf; Becker, Christian; Simard, Jefrrey R.; Getlik, Matthäus; Bohlke, Nina; Janning, Petra; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2012-06-06
Title of Journal: Journal of the American Chemical Society
Volume: 134
Issue / Number: 22
Start Page: 9138
End Page: 9141
Sequence Number of Article: 1
Document Type: Article
ID: 611010.0
Targeting GSK3 from Ustilago maydis: Type-II Kinase Inhibitors
as Potential Antifungals
Authors: Grütter, Christian; Simard, Jeffrey R.; Mayer-Wrangowski, Svenja C.; Schreier, Peter H.; Pérez-Martín, José; Richters, André; Getlik, Matthäus; Gutbrod, Oliver; Braun, Christoph A.; Beck, Michael E.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2012-04-30
Title of Journal: ACS Chemical Biology
Volume: 7
Issue / Number: 7
Start Page: 1257
End Page: 1267
Sequence Number of Article: 1
Document Type: Article
ID: 614971.0
A Chemical Genetic Approach for Covalent Inhibition of Analogue-Sensitive Aurora Kinase
Authors: Koch, André; Rode, Haridas B.; Richters, André; Rauh, Daniel; Hauf, Silke
Date of Publication (YYYY-MM-DD): 2012
Title of Journal: ACS Chemical Biology
Volume: 7
Issue / Number: 4
Start Page: 723
End Page: 731
Sequence Number of Article: 1
Document Type: Article
ID: 609652.0
Synthese und biochemische Charakterisierung kovalenter Kinase-Inhibitoren zur Umgehung der Wirkstoffresistenz T790M in EGFR
Authors: Engel, Julian
Type of Thesis (e.g.Diploma): master
Date of Approval (YYYY-MM-DD): 2011-09-12
Name of University: Technische Universität Dortmund
Place of University: Dortmund
Document Type: Thesis
ID: 576619.0
Entries: 1-10  
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