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          Institute: MPI für neurologische Forschung     Collection: Emeritus-Collection Prof. Heiss     Display Documents



ID: 13398.0, MPI für neurologische Forschung / Emeritus-Collection Prof. Heiss
The ECAT HRRT: Performance and first clinical application of the new high resolution research tomograph
Authors:Wienhard, Klaus; Schmand, Matthias; Casey, M. E.; Baker, K.; Bao, J.; Eriksson, L.; Jones, W. F.; Knoess, C.; Lenox, M.; Lercher, M.; Luk, P.; Michel, C.; Reed, J. H.; Richerzhagen, Norbert; Treffert, J.; Vollmar, Stefan; Young, J. W.; Heiss, Wolf-Dieter; Nutt, R.
Language:English
Date of Publication (YYYY-MM-DD):2002-02
Title of Journal:IEEE Transactions on Nuclear Science
Journal Abbrev.:IEEE Trans. Nucl. Sci.
Volume:49
Issue / Number:1
Start Page:104
End Page:110
Copyright:Copyright 2002 IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
Review Status:Peer-review
Audience:Experts Only
Abstract / Description:The ECAT HRRT is a three-dimensional (3-D) only dedicated brain tomograph employing the new scintillator lutetium-oxy- orthosilicate (LSO) and using depth of interaction (DOI) information to achieve uniform isotropic resolution across a 20-cm diameter volume. With its unique technological innovations it represents the prototype of a new generation of high-resolution brain tomographs. The physical performance with respect to count rate, live time, scatter, sensitivity, and resolution was evaluated with phantom studies and measurements with a point source. The HRRTs imaging performance was tested with phantoms and fluorodeoxyglucose (FDG) scans performed in animal and human brains. We find that due to the significantly improved resolution and the large solid angle covered by the panel detectors, several Issues that have been adequately solved for older generation scanners demand new attention for the HRRT, like acquiring and handling large amounts of data effectively, strategies for optimal reconstruction, shielding, and correction of random coincidences.
Free Keywords:brain tomograph; depth of interaction (DOI); lutetium-oxy- orthosilicate (LSO); phoswitch detector; positron emission tomography (PET)
Comment of the Author/Creator:Date: 2002, FEB
External Publication Status:published
Document Type:Article
Communicated by:N. N.
Affiliations:MPI für neurologische Forschung/Allgemeine Neurologie (PET) - Abt. Prof. Heiss/Arbeitsgruppe Prof. Wienhardt
External Affiliations:Max Planck Inst Neurol Res, Gleueler Str 50, D-5043 Cologne,; Germany; Max Planck Inst Neurol Res, D-5043 Cologne, Germany; CTI PET Syst Inc, Knoxville, TN 37932 USA; Karolinska Inst, S-17176 Stockholm, Sweden; Catholic Univ Louvain, PET Lab, B-1348 Louvain, Belgium; CTI Inc, Knoxville, TN 37432 USA
Identifiers:ISI:000175427300018 [ID No:1]
ISSN:0018-9499 [ID No:2]
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