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          Institute: MPI für biophysikalische Chemie     Collection: Abteilungsunabhängige Arbeitsgruppen     Display Documents



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ID: 16680.0, MPI für biophysikalische Chemie / Abteilungsunabhängige Arbeitsgruppen
Expression of a linker histone-like gene in the primordial germ cells in zebrafish
Authors:Mueller, K.; Thisse, C.; Thisse, B.; Raz, E.
Language:English
Date of Publication (YYYY-MM-DD):2002-09
Title of Journal:Mechanisms of Development
Volume:117
Issue / Number:1-2
Start Page:253
End Page:257
Review Status:Peer-review
Audience:Not Specified
Abstract / Description:Similar to many other organisms, specification of primordial germ cells (PGCs) in zebraftsh occurs during early development and depends on inheritance of 'germ plasm' determinants. Following their specification, the PGCs exhibit characteristic transcriptional profile and cell behaviour. Here we describe the cloning, expression pattern and sub-cellular localization of the zebrafish H I type linker histone, HIM, which is specifically expressed in the PGCs in the second phase of their development. HIM transcripts are uniformly distributed during blastula stages, but become restricted to the PGCs during gastrulation and remain visible in PGCs as they migrate towards the region of the gonad. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
Free Keywords:zebrafish; linker histone; H1M; primordial germ cell
Comment of the Author/Creator:Date: 2002, SEP
External Publication Status:published
Document Type:Article
Communicated by:N. N.
Affiliations:MPI für biophysikalische Chemie/AG Erez Raz
External Affiliations:ULP, INSERM, CNRS, Inst Genet & Biol Mol & Cellulaire, F-67404 Illkirch Graffenstaden, France
Identifiers:URL:http://www.sciencedirect.com/science?_ob=MImg&_ima...
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