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          Institute: MPI für experimentelle Endokrinologie     Collection: Abteilung Eichele     Display Documents



  history
ID: 214433.0, MPI für experimentelle Endokrinologie / Abteilung Eichele
GenePaint.org: an atlas of gene expression patterns in the mouse embryo
Authors:Visel, A.; Thaller, C.; Eichele, G.
Language:English
Date of Publication (YYYY-MM-DD):2004-01-01
Title of Journal:Nucleic Acids Res
Volume:32
Issue / Number:Database issue
Start Page:D552
End Page:6
Review Status:Peer-review
Audience:Experts Only
Abstract / Description:High-throughput instruments were recently developed to determine gene expression patterns on tissue sections by RNA in situ hybridization. The resulting images of gene expression patterns, chiefly of E14.5 mouse embryos, are accessible to the public at http://www.genepaint.org. This relational database is searchable for gene identifiers and RNA probe sequences. Moreover, patterns and intensity of expression in approximately 100 different embryonic tissues are annotated and can be searched using a standardized catalog of anatomical structures. A virtual microscope tool, the Zoom Image Server, was implemented in GenePaint.org and permits interactive zooming and panning across approximately 15,000 high-resolution images.
Free Keywords:Animals
; Brain/metabolism
; Computational Biology
; *Databases, Genetic
; Embryo/*metabolism
; *Gene Expression Profiling
; *Gene Expression Regulation, Developmental
; *In Situ Hybridization
; Information Storage and Retrieval
; Internet
; Mice/*embryology/*genetics
; RNA Probes/genetics
; RNA, Messenger/analysis/genetics
; Research Support, Non-U.S. Gov't
; Research Support, U.S. Gov't, P.H.S.
; Software
External Publication Status:published
Document Type:Article
Affiliations:MPI für experimentelle Endokrinologie
Identifiers:URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=... [ID No:1]
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