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          Institute: MPI für molekulare Pflanzenphysiologie     Collection: Publikationen Pflanzenphysiologie     Display Documents

ID: 228847.0, MPI für molekulare Pflanzenphysiologie / Publikationen Pflanzenphysiologie
Potential of metabolomics as a functional genomics tool
Authors:Bino, R. J.; Hall, R. D.; Fiehn, O.; Kopka, J; Saito, K.; Draper, J.; Nikolau, B. J.; Mendes, P.; Roessner-Tunali, U.; Beale, M. H.; Trethewey, R. N.; Lange, B. M.; Wurtele, E. S.; Sumner, L. W.
Date of Publication (YYYY-MM-DD):2004-09
Title of Journal:Trends in Plant Science
Journal Abbrev.:Trends Plant Sci
Issue / Number:9
Start Page:418
End Page:425
Review Status:not specified
Audience:Not Specified
Abstract / Description:Metabolomics is developing as an important functional genomics tool; however, there is still room for technical improvements in both the large-scale determination of metabolites from complex plant tissues and the dissemination of metabolomics research data. For the continued maturation of metabolomics, the following three objectives need to be achieved: (i) improvement in the comprehensive coverage of the plant metabolome, (ii) facilitation of comparison of results between laboratories and experiments, and (iii) enhancement of the integration of metabolomic data with other functional genomic information. Because these challenges are widely recognized and endorsed, we propose community-based efforts to define common criteria and to initiate concerted actions directed towards the release of standard reference materials, construction of consolidated metabolite libraries, and development of metabolite-specific data-management systems.
Free Keywords:mass-spectrometry
; systems biology
; secondary metabolites
; arabidopsis-thaliana
; plant metabolomics
; potato-tuber
; database
; chromatography
; information
; proteomics
External Publication Status:published
Document Type:Article
Communicated by:N. N.
Affiliations:MPI für molekulare Pflanzenphysiologie/Molekulare Physiologie/AG Fiehn
External Affiliations:Univ Wageningen & Res Ctr, Dept Plant Physiol, Arboretumlaan 4, NL-6703 BD Wageningen, Netherlands
Univ Wageningen & Res Ctr, Dept Plant Physiol, NL-6703 BD Wageningen, Netherlands
Plant Res Int BV, NL-6700 AA Wageningen, Netherlands
Ctr Biosyst Genom, NL-6700 AB Wageningen, Netherlands
Max Planck Inst Mol Plant Physiol, D-14424 Potsdam, Germany
Chiba Univ, Grad Sch Pharmaceut Sci, Inage Ku, Chiba 2638522, Japan
Univ Wales, Inst Biol Sci, Aberystwyth SY23 3DA, Dyfed, Wales
Iowa State Univ Sci & Technol, Ctr Designer Crops, Ames, IA 50011 USA
Virginia Polytech Inst & State Univ, Virginia Bioinformat Inst, Blacksburg, VA 24061 USA
Univ Melbourne, Sch Bot, Australian Ctr Plant Funct Genom, Melbourne, Vic 3010, Australia
Rothamsted Expt Stn, Natl Ctr Platn & Microbial Metabolom, Harpenden AL5 2JQ, Herts, England
Metanom GmbH & Co KGaA, D-10589 Berlin, Germany
Washington State Univ, Inst Biol Chem, Pullman, WA 99164 USA
Iowa State Univ, Dept Genet Dev & Cell Biol, Ames, IA USA
Samuel Roberts Noble Fdn Inc, Div Plant Biol, Ardmore, OK 73401 USA
Identifiers:ISI:000224185400002 [ID No:1]
ISI:000224185400002 [ID No:2]
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