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          Institute: MPI für molekulare Pflanzenphysiologie     Collection: Publikationen Pflanzenphysiologie     Display Documents



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ID: 251394.0, MPI für molekulare Pflanzenphysiologie / Publikationen Pflanzenphysiologie
Improving the levels of essential amino acids and sulfur metabolites in plants
Authors:Galili, G.; Amir, R.; Hoefgen, R.; Hesse, H.
Language:English
Date of Publication (YYYY-MM-DD):2005-09
Title of Journal:Biological Chemistry
Journal Abbrev.:Biol Chem
Volume:386
Issue / Number:9
Start Page:817
End Page:831
Review Status:not specified
Audience:Not Specified
Abstract / Description:Plants represent the major source of food for humans, either directly or indirectly through their use as livestock feeds. Plant foods are not nutritionally balanced because they contain low proportions of a number of essential metabolites, such as vitamins and amino acids, which humans and a significant proportion of their livestock cannot produce on their own. Among the essential amino acids needed in human diets, Lys, Met, Thr and Trp are considered as the most important because they are present in only low levels in plant foods. In the present review, we discuss approaches to improve the levels of the essential amino acids Lys and Met, as well as of sulfur metabolites, in plants using metabolic engineering approaches. We also focus on specific examples for which a deeper understanding of the regulation of metabolic networks in plants is needed for tailor-made improvements of amino acid metabolism with minimal interference in plant growth and productivity.
Free Keywords:cysteine
; essential amino acids
; lysine
; metabolic engineering
; methionine
; nutritional quality
; cystathionine-gamma-synthase
; transgenic tobacco plants
; seed storage-protein
; bacterial dihydrodipicolinate synthase
; adenosine 5'-phosphosulfate reductase
; increased lysine synthesis
; acetyl-l-serine
; arabidopsis-thaliana
; cysteine synthase
; methionine biosynthesis
External Publication Status:published
Document Type:Article
Communicated by:N. N.
Affiliations:MPI für molekulare Pflanzenphysiologie/Molekulare Physiologie/AG Hoefgen
External Affiliations:Weizmann Inst Sci, Dept Plant Sci, IL-76100 Rehovot, Israel
Weizmann Inst Sci, Dept Plant Sci, IL-76100 Rehovot, Israel
Migal Galilee Technol Ctr, Plant Sci Lab, IL-11016 Kiryat Shmona, Israel
Max Planck Inst Mol Physiol, Dept Mol Physiol, D-14476 Golm, Germany
Identifiers:ISI:000232274100001 [ID No:1]
ISI:000232274100001 [ID No:2]
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