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Home Search Quick Search Advanced Fulltext Browse Collections Persons My eDoc Session History Login Name: Password: Documentation Help Support Wiki Direct access to document ID:	Institute: MPI für molekulare Genetik     Collection: Department of Computational Molecular Biology     Display Documents   history ID: 267502.0, MPI für molekulare Genetik / Department of Computational Molecular Biology The SYSTERS Protein Family Database in 2005 Authors: Meinel, Thomas; Krause, Antje; Luz, Hannes; Vingron, Martin; Staub, Eike Language: English Title of Journal: Nucleic Acids Research (London) Journal Abbrev.: Nucleic Acids Res Volume: 33 Start Page: D226 End Page: D229 Title of Issue: Database issue Copyright: © 2005, the authors Nucleic Acids Research, Vol. 33, Database issue © Oxford University Press 2005; all rights reserved Review Status: not specified Audience: Experts Only Abstract / Description: The SYSTERS project aims to provide a meaningful partitioning of the whole protein sequence space by a fully automatic procedure. A refined two-step algorithm assigns each protein to a family and a superfamily. The sequence data underlying SYSTERS release 4 now comprise several protein sequence databases derived from completely sequenced genomes (ENSEMBL, TAIR, SGD and GeneDB), in addition to the comprehensive Swiss-Prot/TrEMBL databases. The SYSTERS web server (http://systers.molgen.mpg.de) provides access to 158 153 SYSTERS protein families. To augment the automatically derived results, information from external databases like Pfam and Gene Ontology are added to the web server. Furthermore, users can retrieve pre-processed analyses of families like multiple alignments and phylogenetic trees. New query options comprise a batch retrieval tool for functional inference about families based on automatic keyword extraction from sequence annotations. A new access point, PhyloMatrix, allows the retrieval of phylogenetic profiles of SYSTERS families across organisms with completely sequenced genomes. External Publication Status: published Document Type: Article Communicated by: Martin Vingron Affiliations: MPI für molekulare Genetik External Affiliations: TFH Wildau, Biosystemtechnik/Bioinformatik, Bahnhofstrasse, 15745 Wildau, Germany Identifiers: DOI:10.1093/nar/gki030 OAI:http://nar.oxfordjournals.org/cgi/content/full/33/... Full Text: You have privileges to view the following file(s): D226.pdf  [647,00 Kb]      Meinel et al. - Nucleic Acids Res.pdf  [647,00 Kb]      The scope and number of records on eDoc is subject to the collection policies defined by each institute - see "info" button in the collection browse view.