Home News About Us Contact Contributors Disclaimer Privacy Policy Help FAQ

Home
Search
Quick Search
Advanced
Fulltext
Browse
Collections
Persons
My eDoc
Session History
Login
Name:
Password:
Documentation
Help
Support Wiki
Direct access to
document ID:


          Institute: MPI für molekulare Genetik     Collection: Department of Computational Molecular Biology     Display Documents



ID: 268480.0, MPI für molekulare Genetik / Department of Computational Molecular Biology
SVC: structured visualization of evolutionary sequence conservation
Authors:Roepcke, Stefen; Fiziev, P.; Seeburg, P. H.; Vingron, Martin
Language:English
Date of Publication (YYYY-MM-DD):2005-04-29
Title of Journal:Nucleic Acids Research
Journal Abbrev.:NAR
Volume:33
Start Page:W271
End Page:W273
Title of Issue:Web Server Issue
Copyright:© The Author 2005. Published by Oxford University Press. All rights reserved
The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions@oupjournals.org
Review Status:not specified
Audience:Experts Only
Abstract / Description:We have developed a web application for the detailed analysis and visualization of evolutionary sequence conservation in complex vertebrate genes. Given a pair of orthologous genes, the protein-coding sequences are aligned. When these sequences are mapped back onto their encoding exons in the genomes, a scaffold of the conserved gene structure naturally emerges. Sequence similarity between exons and introns is analysed and embedded into the gene structure scaffold. The visualization on the SVC server provides detailed information about evolutionarily conserved features of these genes. It further allows concise
External Publication Status:published
Document Type:Article
Communicated by:Martin Vingron
Affiliations:MPI für molekulare Genetik
External Affiliations:Max Planck Institute for Medical Research Jahnstrasse 73, 69120 Heidelberg, Germany.
Identifiers:URI:10.1093/nar/gki589
ISSN:0305-1048
Full Text:
You have privileges to view the following file(s):
W271.pdf  [87,00 Kb]   
 
The scope and number of records on eDoc is subject to the collection policies defined by each institute - see "info" button in the collection browse view.