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          Institute: MPI für Meteorologie     Collection: Climate Processes     Display Documents



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ID: 281725.0, MPI für Meteorologie / Climate Processes
Gene therapy for HIV infection: what does it need to make it work?
Authors:von Laer, Dorothee; Hasselmann, Susanne; Hasselmann, Klaus F.
Language:English
Date of Publication (YYYY-MM-DD):2006-06
Title of Journal:Journal of Gene Medicine
Volume:8
Start Page:658
End Page:667
Review Status:Peer-review
Audience:Not Specified
Abstract / Description:The efficacy of antiviral drug therapy for HIV infection is limited by toxicity and viral resistance. Thus, alternative therapies need to be explored. Several gene therapeutic strategies for HIV infection have been developed, but in clinical testing therapeutically effective levels of the transgene product were not achieved. This review focuses on the determinants of therapeutic efficacy and discusses the potential and also the limits of current gene therapy approaches for HIV infection. Copyright © 2006 John Wiley & Sons, Ltd.
External Publication Status:published
Document Type:Article
Affiliations:MPI für Meteorologie/Emeriti
Identifiers:DOI:10.1002/jgm.908
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