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          Institute: MPI für molekulare Physiologie     Collection: Chemical Genomics Center     Display Documents



  history
ID: 315360.0, MPI für molekulare Physiologie / Chemical Genomics Center
Structure-guided development of affinity probes for tyrosine kinases using chemical genetics
Authors:Blair, Jimmy A.; Rauh, Daniel; Kung, Charles; Yun, Cai-Hong; Fan, Qi-Wen; Rode, Haridas; Zhang, Chao; Eck, Michael J.; Weiss, William A.; Shokat, Kevan M.
Language:English
Date of Publication (YYYY-MM-DD):2007-04
Title of Journal:Nature Chemical Biology
Volume:3
Issue / Number:4
Start Page:229
End Page:238
Sequence Number of Article:1
Review Status:Peer-review
Audience:Experts Only
Intended Educational Use:No
Free Keywords:Growth-Factor Receptor; Cell Lung Cancer; Irreversible Inhibitors; C-SRC; Acquired-Resistance; Protein-Kinase; EGF Receptor; GEFITINIB; Mutation; Domain
External Publication Status:published
Document Type:Article
Communicated by:Jürgen Block
Affiliations:MPI für molekulare Physiologie/Chemical Genomics Center of the MPS /AG Dr. Daniel Rauh
External Affiliations:Department of Chemistry, University of California, Berkeley, Berkeley, California 94720, USA.
Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, 600 16th Street, MC 2280, San Francisco, California 94158, USA.
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, 44 Binney Street, Boston, Massachusetts 02115, USA.
Departments of Neurology, Neurological Surgery and Pediatrics, and the Brain Tumor Research Center, University of California, San Francisco, San Francisco, California 94143, USA.
Novartis Institutes of Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA (C.K.).
Identifiers:URL:http://dx.doi.org/10.1038/nchembio866 [article locator with full text links]
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