MPI für Infektionsbiologie / Department of Molecular Biology |
|Correlation of T cell response and bacterial clearance in human volunteers challenged with Helicobacter pylori revealed by randomised controlled vaccination with Ty21a-based Salmonella vaccines|
|Authors:||Aebischer, Toni; Bumann, Dirk; Epple, H. J.; Metzger, Wolfram G.; Schneider, T.; Cherepnev, Georgy; Walduck, Anna; Kunkel, D.; Moos, V.; Loddenkemper, C.; Jiadze, I.; Panasyuk, M.; Stolte, M.; Graham, D. Y.; Zeitz, M.; Meyer, Thomas F.|
|Date of Publication (YYYY-MM-DD):||2008-08|
|Title of Journal:||Gut|
|Issue / Number:||8|
|Copyright:||Copyright © 2008 BMJ Publishing Group Ltd & British Society of Gastroenterology|
|Comment of the Author/Creator:||ACKNOWLEDGEMENTS
We would like to thank S Diescher, M Drabkina, N Gehrmann, K Hoffmann, R Hurwitz, M Kronawitter, S Jackisch, H Mollenkopf, K P Pleissner, M Sörensen and A Zergiebel for expert assistance and technical support, and O Liesenfeld for support in processing of stool samples. This work was supported by grants from the Deutsche Forschungsgemeinschaft, KFO 104 Projects 8 (Bu 971/2-1,2, Ae16/4-4 and Z).
Competing interests: None.
Ethics approval: The study protocols were developed adhering to the Declaration of Helsinki, reviewed and approved by the ethical review board of the Charité, Berlin, and the studies were registered with the responsible German federal authority, the Paul Ehrlich Institute (applications nos 0802/02 and 1097/01).
Patient consent: All volunteers were informed about the study protocol, potential risks and adverse reactions to vaccination and challenge infection before giving written consent.
|External Publication Status:||published|
|Communicated by:||Hilmar Fünning|
|Affiliations:||MPI für Infektionsbiologie/Department of Molecular Biology|
|External Affiliations:||Charite Campus Benjamin Franklin, Med Clin 1, Berlin, Germany.; Charite Campus Benjamin Franklin, Inst Pathol, Berlin, Germany.; Kazan VI Lenin State Univ, Kazan 420008, Russia.; Klinikum Bayreuth, Inst Pathol, Bayreuth, Germany.; Vet Affairs Med Ctr Houston, Houston, TX USA.|
|Identifiers:||ISI:000257646200013 [ID No:1] |
ISSN:0017-5749 [ID No:2]
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