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          Institute: MPI für Infektionsbiologie     Collection: Core Facilites     Display Documents



  history
ID: 404039.0, MPI für Infektionsbiologie / Core Facilites
Proteome analysis of apoptosis signaling by S-trityl-L-cysteine, a potent reversible inhibitor of human mitotic kinesin Eg5
Authors:Kozielski, Frank; Skoufias, Dimitrios A.; Indorato, Rose-Laure; Saoudi, Yasmina; Jungblut, Peter R.; Hustoft, Hanne K.; Strozynski, Margarita; Thiede, Bernd
Language:English
Date of Publication (YYYY-MM-DD):2008-01
Title of Journal:PROTEOMICS
Journal Abbrev.:Proteomics
Volume:8
Issue / Number:2
Start Page:289
End Page:300
Copyright:Copyright © 1999-2009 John Wiley & Sons, Inc. All Rights Reserved.
Review Status:Peer-review
Audience:Experts Only
Free Keywords:apoptosis; kinesin; mitotic arrest; STLC; taxol
Comment of the Author/Creator:We thank Dr. Achim Treumann (Royal College of Surgeons
in Ireland) for reading the manuscript. The authors thank UschiZimny-Arndt and Monika Schmid for excellent technical support. We are grateful to the National Cancer Institute/National Institutes of Health (Drug Synthesis & Chemistry Branch,Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis) for providing us with some of the STLC used in this study. The stable HeLa GFP-a-tubulin cell line is a gift from Dr. Tim J. Yen (Fox Chase Cancer Center, Philadelphia,Pennsylvania 19111, USA). This work has been funded by grants from ARC (Association pour la Recherche sur le Cancer, contract number 3973) and Agence Nationale de la Recherche (grant
NT05-3_42614).
The authors have declared no conflict of interest.
External Publication Status:published
Document Type:Article
Communicated by:Hilmar Fünning
Affiliations:MPI für Infektionsbiologie/Core Facilities
External Affiliations:Univ Oslo, Biotechnol Ctr Oslo, N-0317 Oslo, Norway.; Inst Biol Struct, Lab Proteins Cytosquelette, CEA, CNRS,UJF, Grenoble, France.; Beatson Inst Canc Res, Glasgow G61 1BD, Lanark, Scotland.; Univ Grenoble 1, GIN, INSERM, U836, Grenoble, France.
Identifiers:ISI:000252835900006 [ID No:1]
ISSN:1615-9853 [ID No:2]
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