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          Institute: MPI für biologische Kybernetik     Collection: Biologische Kybernetik     Display Documents



ID: 419886.0, MPI für biologische Kybernetik / Biologische Kybernetik
Synthesis and Characterization of a Smart Contrast Agent Sensitive to Calcium
Authors:Dhingra, K.; Maier, M.E.; Beyerlein, M.; Angelovski, G.; Logothetis, N.K.
Date of Publication (YYYY-MM-DD):2008-06
Title of Journal:Chemical Communications
Volume:29
Start Page:3444
End Page:3446
Audience:Not Specified
Intended Educational Use:No
Abstract / Description:A novel first-generation Ca2+ sensitive contrast agent, Gd-DOPTRA has been synthesized and characterized. The agent shows 100% relaxivity enhancement upon addition of Ca2+. The agent is selective and sensitive to Ca2+ also in the presence of Mg2+ and Zn2+. The relaxivity studies carried out in physiological fluids prove the prospects of the agent for in vivo measurements.
External Publication Status:published
Document Type:Article
Communicated by:Holger Fischer
Affiliations:MPI f�r biologische Kybernetik/Neurophysiology (Dept. Logothetis)
Identifiers:LOCALID:5128
URL:http://www.rsc.org/ej/CC/2008/b801975d.pdf
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