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          Institute: MPI für biophysikalische Chemie     Collection: Abteilung Eichele     Display Documents



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ID: 426872.0, MPI für biophysikalische Chemie / Abteilung Eichele
Expression pattern of the repulsive guidance molecules RGM A, B and C during mouse development.
Authors:Oldekamp, J.; Kraemer, N.; Alvarez-Bolado, G.; Skutella, T.
Language:English
Date of Publication (YYYY-MM-DD):2004-05
Title of Journal:Gene Expression Patterns
Volume:4
Issue / Number:3
Start Page:283
End Page:288
Review Status:not specified
Audience:Not Specified
Abstract / Description:We have characterized for the first time the mouse expression patterns of the three known members of the novel RGM gene family ('Repulsive Axonal Guidance molecules' A, B and C) by in situ hybridization. Both RGM A and B are mostly expressed in central nervous system, while RGM C is exclusively expressed in all striated muscle and in the myocardium. RGM A and B appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGM A appears in the neuroepithelium, and only RGM B in the peripheral nervous system. During development, both RGM A and B appear also in lung and in limb cartilage, while RGM B has additional expression domains in pancreas.
Free Keywords:axonal guidance brain; cochlear epithelium; cranial nerve ganglia; dorsal root ganglia; lung; marker; myocardium; neuroepithelium; pancreas; striated muscle
External Publication Status:published
Document Type:Article
Communicated by:N. N.
Affiliations:MPI für biophysikalische Chemie/Abt. Gregor Eichele
MPI für biophysikalische Chemie/AG Alvarez-Bolado
Identifiers:URL:http://www.sciencedirect.com/science?_ob=MImg&_ima...
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