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          Institute: MPI für Neurobiologie     Collection: Behavioral Genetics     Display Documents

ID: 429905.0, MPI für Neurobiologie / Behavioral Genetics
The Mushroom Body of Adult Drosophila Characterized by GAL4 Drivers
Authors:Aso, Y.; Grübel, K.; Busch, S.; Friedrich, A. B.; Siwanowicz, I.; Tanimoto, H.
Date of Publication (YYYY-MM-DD):2009
Title of Journal:Journal of Neurogenetics
Journal Abbrev.:J. Neurogenet.
Issue / Number:1-2
Start Page:156
End Page:172
Review Status:Peer-review
Audience:Not Specified
Abstract / Description:The mushroom body is required for a variety of behaviors of Drosophila melanogaster. Different types of intrinsic and extrinsic mushroom body neurons might underlie its functional diversity. There have been many GAL4 driver lines identified that prominently label the mushroom body intrinsic neurons, which are known as Kenyon cells. Under one constant experimental condition, we analyzed and compared the the expression patterns of 25 GAL4 drivers labeling the mushroom body. As an internet resource, we established a digital catalog indexing representative confocal data of them. Further more, we counted the number of GAL4-positive Kenyon cells in each line. We found that approximately 2,000 Kenyon cells can be genetically labeled in total. Three major Kenyon cell subtypes, the , '/', and / neurons, respectively, contribute to 33, 18, and 49% of 2,000 Kenyon cells. Taken together, this study lays groundwork for functional dissection of the mushroom body.
Free Keywords:insect brain; morphology; GAL4; UAS system; expression database; Kenyon cells
External Publication Status:published
Document Type:Article
Version Comment:Automatic journal name synchronization
Communicated by:Annegret Cerny
Affiliations:MPI für Neurobiologie/Behavioral Genetics (Tanimoto)
External Affiliations:[Aso, Yoshinori; Grübel, Kornelia; Busch, Sebastian; Tanimoto, Hiromu] Univ Würzburg, Dept Genet & Neurobiol, Würzburg, Germany.
Identifiers:ISI:000264376400019 [ID No:1]
ISSN:0167-7063 [ID No:2]
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