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          Institute: MPI für Infektionsbiologie     Collection: Core Facilites     Display Documents



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ID: 441574.0, MPI für Infektionsbiologie / Core Facilites
Finding one's way in proteomics: a protein species nomenclature
Authors:Schlüter, Hartmut; Apweiler, Rolf; Holzhütter, Hermann-Georg; Jungblut, Peter R.
Language:English
Date of Publication (YYYY-MM-DD):2009-09-09
Title of Journal:Chemistry Central Journal
Volume:3
Sequence Number of Article:11
Copyright:© 2009 Schlüter et al
Review Status:Peer-review
Audience:Experts Only
Abstract / Description:Our knowledge of proteins has greatly improved in recent years, driven by new technologies in the fields of molecular biology and proteome research. It has become clear that from a single gene not only one single gene product but many different ones - termed protein species - are generated, all of which may be associated with different functions. Nonetheless, an unambiguous nomenclature for describing individual protein species is still lacking. With the present paper we therefore propose a systematic nomenclature for the comprehensive description of protein species. The protein species nomenclature is flexible and adaptable to every level of knowledge and of experimental data in accordance with the exact chemical composition of individual protein species. As a minimum description the entry name (gene name + species according to the UniProt knowledgebase) can be used, if no analytical data about the target protein species are available.
External Publication Status:published
Document Type:Article
Communicated by:Hilmar Fünning
Affiliations:MPI für Infektionsbiologie/Core Facilities
External Affiliations:University Medical Centre Hamburg-Eppendorf, Hamburg, Germany; The EMBL Outstation-The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, Great Britain; Charité Berlin, Institut für Biochemie, Berlin, Germany.
Identifiers:ISI:000270753000001 [ID No:1]
ISSN:1752-153X [ID No:2]
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