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          Institute: MPI für Entwicklungsbiologie     Collection: Abteilung 6 - Molecular Biology (D. Weigel)     Display Documents

ID: 460680.0, MPI für Entwicklungsbiologie / Abteilung 6 - Molecular Biology (D. Weigel)
Dual roles of the bZIP transcription factor PERIANTHIA in the control of floral architecture and homeotic gene expression
Authors:Maier, A. T.; Stehling-Sun, S.; Wollmann, H.; Demar, M.; Hong, R. L.; Haubeiss, S.; Weigel, D.; Lohmann, J. U.
Date of Publication (YYYY-MM-DD):2009-05
Title of Journal:Development
Issue / Number:10
Start Page:1613
End Page:1620
Review Status:not specified
Audience:Not Specified
Abstract / Description:Flowers develop from floral meristems, which harbor stem cells that support the growth of floral organs. The MADS domain transcription factor AGAMOUS (AG) plays a central role in floral patterning and is required not only for the specification of the two reproductive organ types, but also for termination of stem cell fate. Using a highly conserved cis-regulatory motif as bait, we identified the bZIP transcription factor PERIANTHIA (PAN) as a direct regulator of AG in Arabidopsis. PAN and AG expression domains overlap, and mutations in either the PAN-binding site or PAN itself abolish the activity of a reporter devoid of redundant elements. Whereas under long-day conditions pan mutants have merely altered floral organ number, they display in addition typical AG loss-of-function phenotypes when grown under short days. Consistently, we found reduced AG RNA levels in these flowers. Finally, we show that PAN expression persists in ag mutant flowers, suggesting that PAN and AG are engaged in a negative-feedback loop, which might be mediated by the stem-cell-inducing transcription factor WUSCHEL (WUS).
Free Keywords:AGAMOUS Protein, Arabidopsis/metabolism; Arabidopsis/anatomy & histology/metabolism/*physiology; Arabidopsis Proteins/genetics/metabolism/*physiology; Body Patterning/*physiology; DNA-Binding Proteins/genetics/*physiology; Feedback, Physiological; Flowers/anatomy & histology/metabolism/*physiology; Gene Expression Regulation, Plant; Homeodomain Proteins/metabolism; Mutation; Stem Cells/cytology/physiology; Transcription Factors/genetics/*physiology
External Publication Status:published
Document Type:Article
Affiliations:MPI für Entwicklungsbiologie/Abteilung 6 - Molekulare Biologie (Detlef Weigel)
External Affiliations:%G eng
Identifiers:ISSN:0950-1991 (Print) 0950-1991 (Linking) %R 136/10/16... [ID No:1]
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=... [ID No:2]
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