Home News About Us Contact Contributors Disclaimer Privacy Policy Help FAQ

Home
Search
Quick Search
Advanced
Fulltext
Browse
Collections
Persons
My eDoc
Session History
Login
Name:
Password:
Documentation
Help
Support Wiki
Direct access to
document ID:


          Institute: MPI für molekulare Zellbiologie und Genetik     Collection: Publikationen MPI-CBG 2009 arch     Display Documents



ID: 463229.0, MPI für molekulare Zellbiologie und Genetik / Publikationen MPI-CBG 2009 arch
Morphological homeostasis by autophagy
Authors:Lingwood, Daniel; Schuck, Sebastian; Ferguson, Charles; Gerl, Mathias; Simons, Kai
Date of Publication (YYYY-MM-DD):2009
Title of Journal:Autophagy
Volume:5
Issue / Number:7
Start Page:1039
End Page:1040
Copyright:not available
Audience:Experts Only
Intended Educational Use:No
Abstract / Description:With cellular organelles coming in all shapes and sizes, the principle 'form follows function' is readily discernible through the cytologist's lens. Architecturally, one might ask whether there is feedback in this organization. Does a cell 'know' when it has constructed membrane into the stacks of the Golgi, the cisternae of the mitochondria or the tubules of the endoplasmic reticulum? Proofreading can occur in vivo as both errors in nucleic acids and misfolds in proteins are recognized by the cell. Are there analogous systems which maintain/regulate the architectural integrity of organelles? Our recent paper entitled Generation of cubic membranes from controlled homotypic interactions of membrane proteins in the endoplasmic reticulum suggests that autophagy may play such a role.
External Publication Status:published
Document Type:Article
Communicated by:n.n.
Affiliations:MPI für molekulare Zellbiologie und Genetik
Identifiers:LOCALID:1368
The scope and number of records on eDoc is subject to the collection policies defined by each institute - see "info" button in the collection browse view.