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| ID:
477338.0,
MPI für molekulare Physiologie / Sonstige wissenschaftliche Organisationseinheiten |
| Stabilizing a Weak Binding State for Effectors in the Human Ras Protein by Cyclen Complexes |
| Authors: | Rosnizeck, Ina C.; Graf, Thorsten; Spoerner, Michael; Tränkle, Jens; Filchtinski, Daniel; Herrmann, Christian; Gremer, Lothar; Vetter, Ingrid R.; Wittinghofer, Alfred; König, Burkhard; Kalbitzer, Hans Robert | | Language: | English | | Date of Publication (YYYY-MM-DD): | 2010 | | Title of Journal: | Angewandte Chemie International Edition | | Volume: | 49 | | Issue / Number: | 22 | | Start Page: | 3830 | | End Page: | 3833 | | Sequence Number of Article: | 1 | | Review Status: | Peer-review | | Audience: | Experts Only | | Intended Educational Use: | No | | Free Keywords: | cyclen; drug design; NMR spectroscopy; Ras protein; signal tranduction | | External Publication Status: | published | | Document Type: | Article |
| Communicated by: | Jürgen Block | | Affiliations: | MPI für molekulare Physiologie/Sonstige Wissenschaftliche Organisationseinheiten/Emeritus-AG: Prof. Dr. Alfred Wittinghofer
MPI für molekulare Physiologie/Abteilung I - Mechanistische Zellbiologie/AG Kristallographie-Dr. I. Vetter
| | External Affiliations: | Universität Regensburg, Institut für Biophysik und Physikalische Biochemie, Universitätsstrasse 31, 93053 Regensburg (Germany)
Ruhr-Universität Bochum, Institut für Physikalische Chemie I, Universitätsstrasse 150, 44780 Bochum (Germany)
Universität Regensburg, Institut für Organische Chemie, Universitätsstrasse 31, 93053 Regensburg (Germany)
| | Identifiers: | URL:http://dx.doi.org/10.1002/anie.200907002 [article locator with full text links] | |
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