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          Institute: MPI für molekulare Physiologie     Collection: Chemical Genomics Center     Display Documents



  history
ID: 525509.0, MPI für molekulare Physiologie / Chemical Genomics Center
Characterization of Irreversible Kinase Inhibitors by Directly Detecting Covalent Bond Formation: A Tool for Dissecting Kinase Drug Resistance
Authors:Klüter, Sabine; Simard, Jeffrey R.; Rode, Haridas B.; Grütter, Christian; Pawar, Vijaykumar; Raaijmakers, Hans C A.; Barf, Tjeerd A.; Rabiller, Matthias; van Otterlo, Willem A. L.; Rauh, Daniel
Language:English
Date of Publication (YYYY-MM-DD):2010-12-10
Title of Journal:ChemBioChem
Volume:11
Issue / Number:18
Start Page:2557
End Page:2566
Sequence Number of Article:1
Review Status:Peer-review
Audience:Experts Only
Intended Educational Use:No
Free Keywords:cancer; drug resistant kinases; EGFR; fluorescence spectroscopy; irreversible inhibitors
External Publication Status:published
Document Type:Article
Communicated by:Jürgen Block
Affiliations:MPI für molekulare Physiologie/Chemical Genomics Center of the MPS /AG Dr. Daniel Rauh
External Affiliations:MSD, Department of Molecular Design and Informatics P.O.Box 20, 5340 BH Oss (The Netherlands)
Molecular Sciences Institute, School of Chemistry, University of Witwatersrand, Johannesburg (South Africa)
Department of Chemistry and Polymer Science, Stellenbosch University 7600 Stellenbosch (South Africa)
Identifiers:URL:http://dx.doi.org/10.1002/cbic.201000352 [article locator with full text links]
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