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          Institute: MPI für molekulare Genetik     Collection: Sequencing Group     Display Documents

ID: 533722.0, MPI für molekulare Genetik / Sequencing Group
Plasticity of animal genome architecture unmasked by rapid evolution of a pelagic tunicate
Authors:Denoeud, France; Henriet, Simon; Mungpakdee, Sutada; Aury, Jean-Marc; Da Silva, Corinne; Brinkmann, Henner; Mikhaleva, Jana; Olsen, Lisbeth Charlotte; Jubin, Claire; Cañestro, Cristian; Bouquet, Jean-Marie; Danks, Gemma; Poulain, Julie; Campsteijn, Coen; Adamski, Marcin; Cross, Ismael; Yadetie, Fekadu; Muffato, Matthieu; Louis, Alexandra; Butcher, Stephen; Tsagkogeorga, Georgia; Konrad, Anke; Singh, Sarabdeep; Jensen, Marit Flo; Cong, Evelyne Huynh; Eikeseth-Otteraa, Helen; Noel, Benjamin; Anthouard, Véronique; Porcel, Betina M.; Kachouri-Lafond, Rym; Nishino, Atsuo; Ugolini, Matteo; Chourrout, Pascal; Nishida, Hiroki; Aasland, Rein; Huzurbazar, Snehalata; Westhof, Eric; Delsuc, Frédéric; Lehrach, Hans; Reinhardt, Richard; Weissenbach, Jean; Roy, Scott W.; Artiguenave, François; Postlethwait, John H.; Manak, J. Robert; Thompson, Eric M.; Jaillon, Olivier; Du Pasquier, Louis; Boudinot, Pierre; Liberles, David A.; Volff, Jean-Nicolas; Philippe, Hervé; Lenhard, Boris; Roest Crollius, Hugues; Wincker, Patrick; Chourrout, Daniel
Date of Publication (YYYY-MM-DD):2010-12-03
Title of Journal:Science
Issue / Number:6009
Start Page:1381
End Page:1385
Copyright:© 2010 American Association for the Advancement of Science
Review Status:not specified
Audience:Experts Only
Abstract / Description:Genomes of animals as different as sponges and humans show conservation of global architecture. Here we show that multiple genomic features including transposon diversity, developmental gene repertoire, physical gene order, and intron-exon organization are shattered in the tunicate Oikopleura, belonging to the sister group of vertebrates and retaining chordate morphology. Ancestral architecture of animal genomes can be deeply modified and may therefore be largely nonadaptive. This rapidly evolving animal lineage thus offers unique perspectives on the level of genome plasticity. It also illuminates issues as fundamental as the mechanisms of intron gain.
Comment of the Author/Creator:E-mail: Daniel.Chourrout@sars.uib.no; wincker@genoscope.cns.fr
External Publication Status:published
Document Type:Article
Communicated by:Richard Reinhardt
Affiliations:MPI für molekulare Genetik
External Affiliations:Commissariat à l’Énergie Atomique, Institut de Génomique, Genoscope, Evry, France.
CNRS, UMR 8030, Evry, France.
Université d’Evry, Evry, France.
Sars International Centre for Marine Molecular Biology, University of Bergen, Bergen, Norway.
Département de Biochimie, Université de Montréal, Montréal, Canada.
Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA.
Bergen Center for Computational Science, University of Bergen, Bergen, Norway.
Laboratorio de Genética, Universidad de Cádiz, Cádiz, Spain.
Dyogen Lab, Institut de Biologie de l’ENS (IBENS), CNRS-UMR8197, Ecole Normale Supérieure, Paris, France.
Department of Biology, University of Iowa, Iowa City,IA 52242–1324, USA.
Laboratoire de Paléontologie, Phylogénie et Paléobiologie, Institut des Sciences de l’Evolution, UMR 5554–CNRS, Université Montpellier II, Montpellier, France.
Department of Statistics, University of Wyoming, Laramie, WY 82071, USA.
Institut de Biologie Cellulaire et Moléculaire du CNRS, Université de Strasbourg, Strasbourg, France.
Department of Biological Sciences, Osaka University, Osaka, Japan.
Centre Hospitalier d’Albi, Albi, France.
Department of Molecular Biology, University of Bergen, Bergen, Norway.
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
Department of Biology, University of Bergen, Bergen, Norway.
Institute of Zoology and Evolutionary Biology, University of Basel, Basel, Switzerland.
Institut National de la Recherche Agronomique (INRA), Virologie et Immunologie Moléculaires, Jouy-en-Josas, France.
Department of Molecular Biology, University of Wyoming, Laramie, WY 82071, USA.
Institut de Génomique Fonctionnelle de Lyon, UMR 5242–CNRS/INRA/Université Claude Bernard Lyon 1/Ecole Normale Supérieure, Ecole Normale Supérieure de Lyon, Lyon, France.
Departament de Genètica, Universitat de Barcelona, Spain.
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