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          Institute: MPI für molekulare Genetik     Collection: Department of Vertebrate Genomics     Display Documents



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ID: 548751.0, MPI für molekulare Genetik / Department of Vertebrate Genomics
International network of cancer genome projects
Authors:Hudson, T. J.; Anderson, W.; Artez, A.; Barker, A. D.; Bell, C.; Bernabe, R. R.; Bhan, M. K.; Calvo, F.; Eerola, I.; Gerhard, D. S.; Guttmacher, A.; Guyer, M.; Hemsley, F. M.; Jennings, J. L.; Kerr, D.; Klatt, P.; Kolar, P.; Kusada, J.; Lane, D. P.; Laplace, F.; Youyong, L.; Nettekoven, G.; Ozenberger, B.; Peterson, J.; Rao, T. S.; Remacle, J.; Schäfer, A. J.; Shibata, T.; Stratton, M. R.; Vockley, J. G.; Watanabe, K.; Yang, H.; Yuen, M. M.; Knoppers, B. M.; Bobrow, M.; Cambon-Thomsen, A.; Dressler, L. G.; Dyke, S. O.; Joly, Y.; Kato, K.; Kennedy, K. L.; Nicolas, P.; Parker, M. J.; Rial-Sebbag, E.; Romeo-Casabona, C. M.; Shaw, K. M.; Wallace, S.; Wiesner, G. L.; Zeps, N.; Lichter, P.; Biankin, A. V.; Chabannon, C.; Chin, L.; Clement, B.; de Alava, E.; Degos, F.; Ferguson, M. L.; Geary, P.; Hayes, D. N.; Johns, A. L.; Kasprzyk, A.; Nakagawa, H.; Penny, R.; Piris, M. A.; Sarin, R.; Scarpa, A.; van de Vijver, M.; Futreal, P. A.; Aburatani, H.; Bayes, M.; Botwell, D. D.; Campbell, P. J.; Estivill, X.; Grimmond, S. M.; Gut, I.; Hirst, M.; Lopez-Otin, C.; Majumder, P.; Marra, M.; McPherson, J. D.; Ning, Z.; Puente, X. S.; Ruan, Y.; Stunnenberg, H. G.; Swerdlow, H.; Velculescu, V. E.; Wilson, R. K.; Xue, H. H.; Yang, L.; Spellman, P. T.; Bader, G. D.; Boutros, P. C.; Flicek, P.; Getz, G.; Guigo, R.; Guo, G.; Haussler, D.; Heath, S.; Lehrach, Hans et al
Language:English
Corporate body:The International Cancer Genome Consortium
Date of Publication (YYYY-MM-DD):2010-04-15
Title of Journal:Nature
Volume:464
Issue / Number:7291
Start Page:993
End Page:998
Copyright:© 2010 Nature Publishing Group
Review Status:not specified
Audience:Experts Only
Abstract / Description:The International Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome studies in tumours from 50 different cancer types and/or subtypes that are of clinical and societal importance across the globe. Systematic studies of more than 25,000 cancer genomes at the genomic, epigenomic and transcriptomic levels will reveal the repertoire of oncogenic mutations, uncover traces of the mutagenic influences, define clinically relevant subtypes for prognosis and therapeutic management, and enable the development of new cancer therapies.
Free Keywords:DNA Methylation; DNA Mutational Analysis/trends; Databases, Genetic; Genes, Neoplasm/genetics; Genetics, Medical/organization & administration/trends; Genome, Human/genetics; Genomics/organization & administration/trends; Humans; Intellectual Property; International Cooperation; Mutation; Neoplasms/classification/*genetics/pathology/therapy
External Publication Status:published
Document Type:Article
Communicated by:Hans Lehrach
Affiliations:MPI für molekulare Genetik
Identifiers:ISSN:1476-4687 (Electronic) [ID No:1]
DOI:10.1038/nature08987 [ID No:2]
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