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          Institute: MPI für molekulare Genetik     Collection: Department of Vertebrate Genomics     Display Documents

ID: 549043.0, MPI für molekulare Genetik / Department of Vertebrate Genomics
Plasticity of animal genome architecture unmasked by rapid evolution of a pelagic tunicate
Authors:Denoeud, F.; Henriet, S.; Mungpakdee, S.; Aury, J. M.; Da Silva, C.; Brinkmann, H.; Mikhaleva, J.; Olsen, L. C.; Jubin, C.; Canestro, C.; Bouquet, J. M.; Danks, G.; Poulain, J.; Campsteijn, C.; Adamski, M.; Cross, I.; Yadetie, F.; Muffato, M.; Louis, A.; Butcher, S.; Tsagkogeorga, G.; Konrad, A.; Singh, S.; Jensen, M. F.; Cong, E. H.; Eikeseth-Otteraa, H.; Noel, B.; Anthouard, V.; Porcel, B. M.; Kachouri-Lafond, R.; Nishino, A.; Ugolini, M.; Chourrout, P.; Nishida, H.; Aasland, R.; Huzurbazar, S.; Westhof, E.; Delsuc, F.; Lehrach, H.; Reinhardt, R.; Weissenbach, J.; Roy, S. W.; Artiguenave, F.; Postlethwait, J. H.; Manak, J. R.; Thompson, E. M.; Jaillon, O.; Du Pasquier, L.; Boudinot, P.; Liberles, D. A.; Volff, J. N.; Philippe, H.; Lenhard, B.; Crollius, H. R.; Wincker, P.; Chourrout, D.
Date of Publication (YYYY-MM-DD):2010-12-03
Title of Journal:Science
Issue / Number:6009
Start Page:1381
End Page:1385
Copyright:© 2010 American Association for the Advancement of Science
Review Status:not specified
Audience:Experts Only
Abstract / Description:Genomes of animals as different as sponges and humans show conservation of global architecture. Here we show that multiple genomic features including transposon diversity, developmental gene repertoire, physical gene order, and intron-exon organization are shattered in the tunicate Oikopleura, belonging to the sister group of vertebrates and retaining chordate morphology. Ancestral architecture of animal genomes can be deeply modified and may therefore be largely nonadaptive. This rapidly evolving animal lineage thus offers unique perspectives on the level of genome plasticity. It also illuminates issues as fundamental as the mechanisms of intron gain.
Comment of the Author/Creator:E-mail:
External Publication Status:published
Document Type:Article
Communicated by:Hans Lehrach
Affiliations:MPI für molekulare Genetik
External Affiliations:Commissariat à l’Énergie Atomique, Institut de Génomique, Genoscope, Evry, France
CNRS, UMR 8030, Evry, France
Université d’Evry, Evry, France
Sars International Centre for Marine Molecular Biology, University of Bergen, Bergen, Norway
Département de Biochimie, Université de Montréal, Montréal, Canada
Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA
Bergen Center for Computational Science, University of Bergen, Bergen, Norway
Laboratorio de Genética, Universidad de Cádiz, Cádiz, Spain
Dyogen Lab, Institut de Biologie de l’ENS (IBENS), CNRS-UMR8197, Ecole Normale Supérieure, Paris, France
Department of Biology, University of Iowa, Iowa City, IA 52242–1324, USA
Laboratoire de Paléontologie, Phylogénie et Paléobiologie, Institut des Sciences de l’Evolution, UMR 5554–CNRS, Université Montpellier II, Montpellier, France
Department of Statistics, University of Wyoming, Laramie, WY 82071, USA
Institut de Biologie Cellulaire et Moléculaire du CNRS, Université de Strasbourg, Strasbourg, France
Department of Biological Sciences, Osaka University, Osaka, Japan
Centre Hospitalier d’Albi, Albi, France
Department of Molecular Biology, University of Bergen, Bergen, Norway
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
Department of Biology, University of Bergen, Bergen, Norway
Institute of Zoology and Evolutionary Biology, University of Basel, Basel, Switzerland
Institut National de la Recherche Agronomique (INRA), Virologie et Immunologie Moléculaires, Jouy-en-Josas, France
Department of Molecular Biology, University of Wyoming, Laramie, WY 82071, USA
Institut de Génomique Fonctionnelle de Lyon, UMR 5242–CNRS/INRA/Université Claude Bernard Lyon 1/Ecole Normale Supérieure, Ecole Normale Supérieure de Lyon, Lyon, France
Departament de Genètica, Universitat de Barcelona, Spain
Identifiers:ISSN:1095-9203 (Electronic) [ID No:1]
DOI:10.1126/science.1194167 [ID No:2]
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