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          Institute: MPI für Herz- und Lungenforschung (W. G. Kerckhoff Institut)     Collection: Publikationen des W. G. Kerckhoff-Instituts     Display Documents



ID: 559570.0, MPI für Herz- und Lungenforschung (W. G. Kerckhoff Institut) / Publikationen des W. G. Kerckhoff-Instituts
Resolving cell-cell junctions: lumen formation in blood vessels
Authors:Zeeb, M.; Strilic, B.; Lammert, E.
Title of Journal:Curr Opin Cell Biol
Volume:22
Issue / Number:5
Start Page:626
End Page:32
Audience:Not Specified
Abstract / Description:Formation of a patent vascular lumen is essential for the transport of oxygen, nutrients and waste products to and from tissues. No matter whether the blood vessel arises from vasculogenesis or angiogenesis, endothelial cells (EC) first have to form a cord, which subsequently lumenizes, in order to generate a functional vessel. During these processes, cellular junctions rearrange between adjacent ECs and are involved in EC polarization as a prerequisite for lumen formation. Here we review the role of EC junctions in vascular lumen formation within different vascular beds.
External Publication Status:published
Document Type:Article
Communicated by:N. N.
Affiliations:MPI für physiologische und klinische Forschung
External Affiliations:Institute of Metabolic Physiology, Heinrich-Heine-University, Dusseldorf, Germany.
Identifiers:ISSN:1879-0410 (Electronic) 0955-0674 (Linking)
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=..
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