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          Institute: MPI für Herz- und Lungenforschung (W. G. Kerckhoff Institut)     Collection: Publikationen des W. G. Kerckhoff-Instituts     Display Documents



ID: 559826.0, MPI für Herz- und Lungenforschung (W. G. Kerckhoff Institut) / Publikationen des W. G. Kerckhoff-Instituts
Obstructive sleep apnea in a patient with the Melkersson-Rosenthal syndrome
Authors:Eisele, H. J.; Reichenberger, F.; Mayer, K.; Weissmann, N.; Seeger, W.; Schulz, R.
Title of Journal:Sleep Breath
Volume:14
Issue / Number:3
Start Page:245
End Page:7
Audience:Not Specified
Abstract / Description:INTRODUCTION: Melkersson-Rosenthal syndrome (MRS) is a rare disorder of unknown etiology. It is characterized by the triad of macrocheilitis, peripheral facial palsy, and lingua plicata. CASE REPORT: A 48-year-old nonobese man with a diagnosis of MRS and marked macroglossia was evaluated because of clinically suspected obstructive sleep apnea (OSA). Established causes of OSA such as anatomic abnormalities of the upper airways or the facial skeleton were not present in this patient. Furthermore, hypothyroidism and acromegaly were excluded as underlying diseases. Polysomnography revealed moderate-to-severe OSA. As the swelling of the tongue had been unresponsive to immunosuppressive pharmacotherapy and surgery did not seem to be a reasonable therapeutic option, the patient was finally treated by continuous positive airway pressure therapy. DISCUSSION: To the best of our knowledge, this is the first report of OSA occurring in a patient with MRS.
Free Keywords:Continuous Positive Airway Pressure; Humans; Macroglossia/diagnosis; Magnetic Resonance Imaging; Male; Melkersson-Rosenthal Syndrome/*diagnosis/therapy; Middle Aged; Polysomnography; Sleep Apnea, Obstructive/*diagnosis
External Publication Status:published
Document Type:Article
Communicated by:N. N.
Affiliations:MPI für physiologische und klinische Forschung
External Affiliations:University of Giessen Lung Center, Giessen, Germany.
Identifiers:ISSN:1522-1709 (Electronic) 1520-9512 (Linking)
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=..
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