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          Institute: MPI für Entwicklungsbiologie     Collection: Abteilung 6 - Molecular Biology (D. Weigel)     Display Documents



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ID: 561637.0, MPI für Entwicklungsbiologie / Abteilung 6 - Molecular Biology (D. Weigel)
STIMPY mediates cytokinin signaling during shoot meristem establishment in Arabidopsis seedlings
Authors:Skylar, A.; Hong, F. X.; Chory, J.; Weigel, D.; Wu, X. L.
Date of Publication (YYYY-MM-DD):2010-02-15
Title of Journal:Development
Volume:137
Issue / Number:4
Start Page:541
End Page:549
Review Status:not specified
Audience:Not Specified
Abstract / Description:The establishment of the primary meristems through proliferation after germination is essential for plant post-embryonic development. Cytokinins have long been considered a key regulator of plant cell division. Here we show that cytokinins are essential for early seedling development of Arabidopsis. Loss of cytokinin perception leads to a complete failure of meristem establishment and growth arrest after germination. We also present evidence that cytokinin signaling is involved in activation of the homeobox gene STIMPY (STIP or WOX9) expression in meristematic tissues, which is essential for maintaining the meristematic fate. Cytokinin-independent STIP expression is able to partially compensate for the shoot apical meristem growth defects in mutants that cannot sense cytokinin. These findings identify a new branch of the cytokinin signaling network, linking cytokinin to the process of meristem and seedling establishment.
Free Keywords:arabidopsis; stimpy; cytokinin signaling; meristem; gene-expression system; b response regulators; apical-basal axis; root-meristem; transcription factors; cell-differentiation; hobbit gene; plants; maintenance; thaliana
External Publication Status:published
Document Type:Article
Affiliations:MPI für Entwicklungsbiologie/Abteilung 6 - Molekulare Biologie (Detlef Weigel)
External Affiliations:Univ So Calif, Los Angeles, CA 90089 USA Univ So Calif, Los Angeles, CA 90089 USA Univ So Calif, Los Angeles, CA 90089 USA Harvard Univ, Sch Publ Hlth, Dana Farber Canc Inst, Dept Biostat & Computat Biol, Boston, MA 02115 USA Salk Inst Biol Studies, Plant Biol Lab, La Jolla, CA 92037 USA Salk Inst Biol Studies, Howard Hughes Med Inst, La Jolla, CA 92037 USA Max Planck Inst Dev Biol, Dept Mol Biol, D-72076 Tubingen, Germany %G English
Identifiers:ISSN:0950-1991 %R Doi 10.1242/Dev.041426 [ID No:1]
ISI:000274016900002 [ID No:2]
ISI:000274016900002 [ID No:3]
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