Home News About Us Contact Contributors Disclaimer Privacy Policy Help FAQ

Home
Search
Quick Search
Advanced
Fulltext
Browse
Collections
Persons
My eDoc
Session History
Login
Name:
Password:
Documentation
Help
Support Wiki
Direct access to
document ID:


          Institute: MPI für molekulare Physiologie     Collection: Abteilung IV - Chemische Biologie     Display Documents



  history
ID: 570056.0, MPI für molekulare Physiologie / Abteilung IV - Chemische Biologie
The development of a whole-cell based medium throughput screening system for the discovery of human aldosterone synthase (CYP11B2) inhibitors: Old drugs disclose new applications for the therapy of congestive heart failure, myocardial fibrosis and hypertension
Authors:Hakki, Tarek; Hübel, Katja; Waldmann, Herbert; Bernhardt, Rita
Language:English
Date of Publication (YYYY-MM-DD):2011
Title of Journal:Journal of Steroid Biochemistry and Molecular Biology
Volume:125
Start Page:120
End Page:128
Sequence Number of Article:1
Review Status:Peer-review
Audience:Experts Only
Intended Educational Use:No
Free Keywords:CYP11Bs; Hyperaldosteronism; Hypertension; Heart failure; Myocardial fibrosis; Screening system; Drug discovery; Drug recycling
External Publication Status:published
Document Type:Article
Communicated by:Jürgen Block
Affiliations:MPI für molekulare Physiologie/Abteilung IV - Chemische Biologie/AG Prof. Dr. Herbert Waldmann
External Affiliations:Institute of Biochemistry, P.O.Box 151150, Saarland University, D-66041 Saarbrücken, Germany
Identifiers:URL:http://dx.doi.org/10.1016/j.jsbmb.2010.12.011 [article locator with full text links]
The scope and number of records on eDoc is subject to the collection policies defined by each institute - see "info" button in the collection browse view.