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          Institute: MPI für Dynamik komplexer technischer Systeme     Collection: Physical and Chemical Foundations of Process Engineering     Display Documents

ID: 63060.0, MPI für Dynamik komplexer technischer Systeme / Physical and Chemical Foundations of Process Engineering
Effect of the homogeneity of the column set on the performance of a simulated moving bed unit. Part I: Theory
Authors:Mihlbachler, K.; Fricke, J.; Yun, T.; Seidel-Morgenstern, A.; Schmidt-Traub, H.; Guiochon, G.
Date of Publication (YYYY-MM-DD):2001
Title of Journal:Journal of Chromatography A
Issue / Number:1-2
Start Page:49
End Page:70
Review Status:not specified
Audience:Experts Only
Intended Educational Use:No
Abstract / Description:Although it is impossible to manufacture identical columns for use in a simulated moving bed (SMB) process, theoretical studies assume that all the columns in a SMB unit have identical characteristics. In practice, calculations in modeling and optimization studies are made with the average values of each column parameter set. In this report, the effects on SMB process performance caused by column-to-column fluctuations of the parameters are discussed. As a first step, we show how the differences in porosity of the columns may be taken into account with a revised set of separation conditions. Reductions in the purity of the extract and the raffinate streams are quantitatively related to the column-to-column fluctuations of the retention times of the two components arising from these porosity differences. For the sake of simplicity, the discussion first addresses the case of a four-column SMB operating under linear conditions. Then, the scope is extended to the cases of SMB units incorporating several columns in each section and to SMB units operating under nonlinear conditions.
External Publication Status:published
Document Type:Article
Communicated by:Andreas Seidel-Morgenstern
Affiliations:MPI für Dynamik komplexer technischer Systeme/Physical and Chemical Foundations of Process Engineering
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