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          Institute: MPI für medizinische Forschung     Collection: Jahbruch 2014_archival     Display Documents

ID: 681431.0, MPI für medizinische Forschung / Jahbruch 2014_archival
Toward unsupervised single−shot diffractive imaging of heterogeneous particles using X−ray free−electron lasers
Translation of Title:Toward unsupervised single−shot diffractive imaging of heterogeneous particles using X−ray free−electron lasers
Authors:Park, Hyung Joo; Loh, Ne−Te Duane; Sierra, Raymond G.; Hampton, Christina Y.; Starodub, Dmitri; Martin, Andrew V.; Barty, Anton; Aquila, Andrew; Schulz, Joachim; Steinbrener, Jan; Shoeman, Robert L.; Lomb, Lukas; Kassemeyer, Stephan; Bostedt, Christoph; Bozek, John; Epp, Sascha W.; Erk, Benjamin; Hartmann, Robert; Rolles, Daniel; Rudenko, Artem; Rudek, Benedikt; Foucar, Lutz; Kimmel, Nils; Weidenspointner, Georg; Hauser, Günter; Holl, Peter; Pedersoli, Emanuele; Liang, Mengning; Hunter, Mark S.; Gumprecht, Lars; Coppola, Nicola; Wunderer, Cornelia; Graafsma, Heinz; Maia, Filipe R. N. C.; Ekeberg, Tomas; Hantke, Max; Fleckenstein, Holger; Hirsemann, Helmut; Nass, Karol; Tobias, Herbert J.; Farquar, George R.; Benner, W. Henry; Hau−Riege, Stesan P.; Reich, Christian; Hartmann, Andreas; Soltau, Heike; Marchesini, Stefano; Bajt, Saša; Barthelmess, Miriam; Strüder, Lothar; Ullrich, Joachim; Bucksbaum, Phillip; Frank, Matthias; Schlichting, Ilme; Chapman, Henry N.; Bogan, Michael J.; Elser, Veit
Date of Publication (YYYY-MM-DD):2013-11-14
Title of Journal:Optics Express
Journal Abbrev.:Optics Express
Issue / Number:23
Start Page:28729
End Page:28742
Review Status:Peer-review
Audience:Experts Only
Intended Educational Use:No
Abstract / Description:Single shot diffraction imaging experiments via X−ray free−electron lasers can generate as many as hundreds of thousands of diffraction patterns of scattering objects. Recovering the real space contrast of a scattering object from these patterns currently requires a reconstruction process with user guidance in a number of steps, introducing severe bottlenecks in data processing. We present a series of measures that replace user guidance with algorithms that reconstruct contrasts in an unsupervised fashion. We demonstrate the feasibility of automating the reconstruction process by generating hundreds of contrasts obtained from soot particle diffraction experiments
External Publication Status:published
Document Type:Article
Communicated by:wkaiser
Affiliations:MPI für medizinische Forschung/Abteilung Biophysik
MPI für medizinische Forschung/Abteilung Biomolekulare Mechanismen
MPI für medizinische Forschung/Abteilung Biomolekulare Mechanismen/Analytical Protein Biochemistry
MPI für medizinische Forschung/Abteilung Biomolekulare Mechanismen/Coherent diffractive imaging
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