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          Institute: MPI für experimentelle Medizin     Collection: Neurogenetics     Display Documents



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ID: 696122.0, MPI für experimentelle Medizin / Neurogenetics
Polytherapy with a combination of three repurposed drugs (PXT3003) down-regulates Pmp22 over-expression and improves myelination, axonal and functional parameters in models of CMT1A neuropathy
Authors:Chumakov, Ilya; Milet, Aude; Cholet, Nathalie; Primas, Gwenal; Boucard, Aurlie; Pereira, Yannick; Graudens, Esther; Mandel, Jonas; Laffaire, Julien; Foucquier, Julie; Glibert, Fabrice; Bertrand, Viviane; Nave, Klaus-Armin; Sereda, Michael W.; Vial, Emmanuel; Guedj, Mickal; Hajj, Rodolphe; Nabirotchkin, Serguei; Cohen, Daniel
Language:English
Date of Publication (YYYY-MM-DD):2014-12-10
Title of Journal:Orphanet Journal of Rare Diseases
Volume:9
Issue / Number:1
Sequence Number of Article:201
Review Status:Peer-review
Audience:Experts Only
Free Keywords:Systems biology; Repurposing; Combination therapy; Baclofen; Naltrexone; Sorbitol; Synergy; CMT1A; Low dose
External Publication Status:published
Document Type:Article
Version Comment:Automatic journal name synchronization
Communicated by:Klaus-Armin Nave
Affiliations:MPI für experimentelle Medizin/Neurogenetics
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