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          Institute: MPI für Entwicklungsbiologie     Collection: Abteilung 3 (bis 2014)- Genetics (C. Nüsslein-Volhard)     Display Documents

ID: 705443.0, MPI für Entwicklungsbiologie / Abteilung 3 (bis 2014)- Genetics (C. Nüsslein-Volhard)
Local reorganization of xanthophores fine-tunes and colors the striped pattern of zebrafish
Authors:Mahalwar, P.; Walderich, B.; Singh, A. P.; Nusslein-Volhard, C.
Date of Publication (YYYY-MM-DD):2014-09-12
Title of Journal:Science
Journal Abbrev.:Science
Issue / Number:6202
Start Page:1362
End Page:1364
Sequence Number of Article:25214630
Review Status:Internal review
Audience:Experts Only
Abstract / Description:The pattern of alternating blue and golden stripes displayed by adult zebrafish is composed of three kinds of pigment cells: black melanophores, yellow xanthophores, and silvery-blue iridophores. We analyzed the dynamics of xanthophores during stripe morphogenesis in vivo with long-term time-lapse imaging. Larval xanthophores start to proliferate at the onset of metamorphosis and give rise to adult xanthophores covering the flank before the arrival of stem-cell-derived iridophores and melanophores. Xanthophores compact to densely cover the iridophores forming the interstripe, and they acquire a loose stellate shape over the melanophores in the stripes. Thus, xanthophores, attracted by iridophores and repelling melanophores, sharpen and color the pattern. Variations on these cell behaviors may contribute to the generation of color pattern diversity in fish.
Free Keywords:Animals; Body Patterning/genetics/*physiology; Chromatophores/cytology/*physiology; Green Fluorescent Proteins/genetics/metabolism; Melanophores/cytology/physiology; PAX7 Transcription Factor/genetics/metabolism; SOXE Transcription Factors/genetics/metabolism; Skin Pigmentation/genetics/*physiology; Time-Lapse Imaging; Zebrafish/*embryology; Zebrafish Proteins/genetics/metabolism
External Publication Status:published
Document Type:Article
Communicated by:MPI für Entwickungsbiologie
Affiliations:MPI für Entwicklungsbiologie/Abteilung 3 - Genetik (Christiane Nüsslein-Volhard)
External Affiliations:Max-Planck-Institut fur Entwicklungsbiologie, Tubingen, Germany. ajeet.singh@tuebingen.mpg.de christiane.nuesslein-volhard@tuebingen.mpg.de.
Identifiers:ISSN:1095-9203 (Electronic) 0036-8075 (Linking) %R 10.1... [ID No:1]
URL:http://www.ncbi.nlm.nih.gov/pubmed/25214630 [ID No:2]
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