Home News About Us Contact Contributors Disclaimer Privacy Policy Help FAQ

Home
Search
Quick Search
Advanced
Fulltext
Browse
Collections
Persons
My eDoc
Session History
Login
Name:
Password:
Documentation
Help
Support Wiki
Direct access to
document ID:


          Institute: MPI für molekulare Zellbiologie und Genetik     Collection: MPI-CBG Publications 2014 (arch)     Display Documents



  history
ID: 705703.0, MPI für molekulare Zellbiologie und Genetik / MPI-CBG Publications 2014 (arch)
The cell biology of neurogenesis: toward an understanding of the development and evolution of the neocortex.
Authors:Taverna, Elena; Götz, Magdalena; Huttner, Wieland B.
Date of Publication (YYYY-MM-DD):2014
Title of Journal:Annual Review of Cell and Developmental Biology
Volume:30
Start Page:465
End Page:502
Copyright:not available
Audience:Experts Only
Intended Educational Use:No
Abstract / Description:Neural stem and progenitor cells have a central role in the development and evolution of the mammalian neocortex. In this review, we first provide a set of criteria to classify the various types of cortical stem and progenitor cells. We then discuss the issue of cell polarity, as well as specific subcellular features of these cells that are relevant for their modes of division and daughter cell fate. In addition, cortical stem and progenitor cell behavior is placed into a tissue context, with consideration of extracellular signals and cell-cell interactions. Finally, the differences across species regarding cortical stem and progenitor cells are dissected to gain insight into key developmental and evolutionary mechanisms underlying neocortex expansion.
External Publication Status:published
Document Type:Article
Version Comment:Automatic journal name synchronization
Communicated by:thuem
Affiliations:MPI für molekulare Zellbiologie und Genetik
Identifiers:LOCALID:6100
The scope and number of records on eDoc is subject to the collection policies defined by each institute - see "info" button in the collection browse view.