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          Institute: MPI für Herz- und Lungenforschung (W. G. Kerckhoff Institut)     Collection: Yearbook_2015     Display Documents



ID: 711932.0, MPI für Herz- und Lungenforschung (W. G. Kerckhoff Institut) / Yearbook_2015
Electrophysiological studies in patients with pulmonary hypertension: a retrospective investigation
Authors:Bandorski, D.; Schmitt, J.; Kurzlechner, C.; Erkapic, D.; Hamm, C. W.; Seeger, W.; Ghofrani, A.; Holtgen, R.; Gall, H.
Date of Publication (YYYY-MM-DD):2014
Title of Journal:Biomed Res Int
Volume:2014
Start Page:617565
Audience:Not Specified
Abstract / Description:Few studies have investigated patients with pulmonary hypertension and arrhythmias. Data on electrophysiological studies in these patients are rare. In a retrospective dual-centre design, we analysed data from patients with indications for electrophysiological study. Fifty-five patients with pulmonary hypertension were included (Dana Point Classification: group 1: 14, group 2: 23, group 3: 4, group 4: 8, group 5: 2, and 4 patients with exercised-induced pulmonary hypertension). Clinical data, 6-minute walk distance, laboratory values, and echocardiography were collected/performed. Nonsustained ventricular tachycardia was the most frequent indication (n = 15) for an electrophysiological study, followed by atrial flutter (n = 14). In summary 36 ablations were performed and 25 of them were successful (atrial flutter 12 of 14 and atrioventricular nodal reentrant tachycardia 4 of 4). Fluoroscopy time was 16 +/- 14.4 minutes. Electrophysiological studies in patients with pulmonary hypertension are feasible and safe. Ablation procedures are as effective in these patients as in non-PAH patients with atrial flutter and atrioventricular nodal reentrant tachycardia and should be performed likewise. The prognostic relevance of ventricular stimulations and inducible ventricular tachycardias in these patients is still unclear and requires further investigation.
External Publication Status:published
Document Type:Article
Communicated by:MPI für Herz- und Lungenforschung
Affiliations:MPI für physiologische und klinische Forschung
External Affiliations:Medical Clinic 1, University Hospital Giessen and Marburg GmbH, Klinikstrasse 33, 35392 Giessen, Germany ; Department of Cardiology, Kerckhoff Heart and Thorax Centre, Benekestrasse 2-8, 61231 Bad Nauheim, Germany. Medical Clinic 1, University Hospital Giessen and Marburg GmbH, Klinikstrasse 33, 35392 Giessen, Germany. Medical Clinic III, St. Agnes Hospital Bocholt, Barloer Weg 125, 46397 Bocholt, Germany. %^ 1435822045
Identifiers:ISSN:2314-6141 (Electronic) %R 10.1155/2014/617565
URL:http://www.ncbi.nlm.nih.gov/pubmed/24977152
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