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Enabling Large-Scale Design, Synthesis and Validation of Small Molecule Protein-Protein Antagonists |
Authors: Koes, D.; Khoury, K.; Huang, Y. J.; Wang, W.; Bista, M.; Popowicz, G. M.; Wolf, S.; Holak, T. A.; Domling, A.; Camacho, C. J. | Date of Publication (YYYY-MM-DD): 2012-03-12 | Title of Journal: PLoS ONE | Volume: 7 | Issue / Number: 3 | Start Page: [1] | End Page: [8] | Sequence Number of Article: e32839 | Document Type: Article | ID: 609523.0 |
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The p53-MDM2/MDMX axis - A chemotype perspective |
Authors: Khoury, K.; Popowicz, G. M.; Holak, T. A.; Domling, A. | Date of Publication (YYYY-MM-DD): 2011-04 | Title of Journal: Medchemcomm | Volume: 2 | Issue / Number: 4 | Start Page: 246 | End Page: 260 | Document Type: Article | ID: 569827.0 |
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The Structure-Based Design of Mdm2/Mdmx-p53 Inhibitors Gets Serious |
Authors: Popowicz, G. M.; Domling, A.; Holak, T. A. | Date of Publication (YYYY-MM-DD): 2011 | Title of Journal: Angewandte Chemie-International Edition | Volume: 50 | Issue / Number: 12 | Start Page: 2680 | End Page: 2688 | Document Type: Article | ID: 561332.0 |
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1,4-Thienodiazepine-2,5-diones via MCR (I): Synthesis, Virtual Space and p53-Mdm2 Activity |
Authors: Huang, Y. J.; Wolf, S.; Bista, M.; Meireles, L.; Camacho, C.; Holak, T. A.; Domling, A. | Date of Publication (YYYY-MM-DD): 2010-08 | Title of Journal: Chemical Biology & Drug Design | Volume: 76 | Issue / Number: 2 | Start Page: 116 | End Page: 129 | Document Type: Article | ID: 493370.0 |
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Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery |
Authors: Popowicz, G. M.; Czarna, A.; Wolf, S.; Wang, K.; Wang, W.; Domling, A.; Holak, T. A. | Date of Publication (YYYY-MM-DD): 2010-03-15 | Title of Journal: Cell Cycle | Volume: 9 | Issue / Number: 6 | Start Page: 1104 | End Page: 1111 | Document Type: Article | ID: 475428.0 |
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