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Entries: 1-10  
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Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity
Authors: Bonn, S.; Herrero, S.; Breitenlechner, C. B.; Erlbruch, A.; Lehmann, W.; Engh, R. A.; Gassel, M.; Bossemeyer, D.
Date of Publication (YYYY-MM-DD): 2006-08-25
Title of Journal: Journal of Biological Chemistry
Volume: 281
Issue / Number: 34
Start Page: 24818
End Page: 24830
Document Type: Article
ID: 287818.0
Crystal structures of active Src kinase domain complexes
Authors: Breitenlechner, C. B.; Kairies, N. A.; Honold, K.; Scheiblich, S.; Koll, H.; Greiter, E.; Koch, S.; Schafer, W.; Huber, R.; Engh, R. A.
Date of Publication (YYYY-MM-DD): 2005-10-21
Title of Journal: Journal of Molecular Biology
Volume: 353
Issue / Number: 2
Start Page: 222
End Page: 231
Document Type: Article
ID: 256276.0
Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase a and mutants
Authors: Breitenlechner, C. B.; Friebe, W. G.; Brunet, E.; Guido, W.; Graul, M.; Thomas, U.; Kunkele, K. P.; Schafer, W.; Gassel, M.; Bosseineyer, D.; Huber, R.; Engh, R. A.; Masjost, B.
Date of Publication (YYYY-MM-DD): 2005-01-13
Title of Journal: Journal of Medicinal Chemistry
Volume: 48
Issue / Number: 1
Start Page: 163
End Page: 170
Document Type: Article
ID: 217857.0
The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A
Authors: Gassel, M.; Breitenlechner, C. B.; Konig, N.; Huber, R.; Engh, R. A.; Bossemeyer, D.
Date of Publication (YYYY-MM-DD): 2004-05-28
Title of Journal: Journal of Biological Chemistry
Volume: 279
Issue / Number: 22
Start Page: 23679
End Page: 23690
Document Type: Article
ID: 222081.0
Structure-based optimization of novel azepane derivatives as PKB inhibitors
Authors: Breitenlechner, C. B.; Wegge, T.; Berillon, L.; Graul, K.; Marzenell, M.; Friebe, W. G.; Thomas, U.; Schumacher, R.; Huber, R.; Engh, R. A.; Masjost, B.
Date of Publication (YYYY-MM-DD): 2004-03-11
Title of Journal: Journal of Medicinal Chemistry
Volume: 47
Issue / Number: 6
Start Page: 1375
End Page: 1390
Document Type: Article
ID: 121672.0
Insights into AGC-kinase inhibitor binding from studies with PKA.
Authors: Bossemeyer, D.; Gassel, M.; Breitenlechner, C. B.; de Vega, S. H.; Engh, R. A.
Date of Publication (YYYY-MM-DD): 2003-09
Title of Journal: Abstracts of Papers of the American Chemical Society
Volume: 226
Start Page: U461
End Page: U461
Document Type: Article
ID: 218241.0
Mutants of protein kinase a that mimic the ATP-binding site of protein kinase B (AKT)
Authors: Gassel, M.; Breitenlechner, C. B.; Ruger, P.; Jucknischke, U.; Schneider, T.; Huber, R.; Bossemeyer, D.; Engh, R. A.
Date of Publication (YYYY-MM-DD): 2003-06-20
Title of Journal: Journal of Molecular Biology
Volume: 329
Issue / Number: 5
Start Page: 1021
End Page: 1034
Document Type: Article
ID: 120379.0
Structural insights into AGC-kinase inhibitor binding from studies with the workhorse PKA
Authors: Gassel, M.; Breitenlechner, C. B.; De Vega, S. H.; Engh, R. A.; Bossemeyer, D.
Date of Publication (YYYY-MM-DD): 2003
Title of Journal: Cellular & Molecular Biology Letters
Volume: 8
Issue / Number: 2A
Start Page: 508
End Page: 509
Document Type: Article
ID: 121664.0
Crystal structure of an altered catalytic subunit of cAMP-dependent protein kinase in complex with the Pkc-kinase inhibitor Bisindolyl-Maleimide 2 in two different conformations - implications for selectivity
Authors: Gaßel, M.; Breitenlechner, C. B.; Engh, R. A.; Bossemeyer, D.
Date of Publication (YYYY-MM-DD): 2003
Title of Journal: Cellular and Molecular Biology Letters
Volume: 8
Start Page: 582
End Page: 582
Document Type: Article
ID: 174618.0
Phosphorylation and flexibility of cyclic-AMP-dependent protein kinase (PKA) using P-31 NMR Spectroscopy
Authors: Seifert, M. H. J.; Breitenlechner, C. B.; Bossemeyer, D.; Huber, R.; Holak, T. A.; Engh, R. A.
Date of Publication (YYYY-MM-DD): 2002-05-14
Title of Journal: Biochemistry
Volume: 41
Issue / Number: 19
Start Page: 5968
End Page: 5977
Document Type: Article
ID: 39339.0
Entries: 1-10  
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