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Entries: 1-10  
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Targeting Gain of Function and Resistance Mutations in Abl and KIT by Hybrid Compound Design
Authors: Richters, André; Ketzer, Julia; Getlik, Matthäus; Grütter, Christian; Schneider, Ralf; Heuckmann, Johannes M.; Heynck, Stefanie; Sos, Martin L.; Gupta, Anu; Unger, Anke; Schultz-Fademrecht, Carsten; Thomas, Roman K.; Bauer, Sebastian; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2013-07-25
Title of Journal: Journal of Medicinal Chemistry
Volume: 56
Issue / Number: 14
Start Page: 5757
End Page: 5772
Sequence Number of Article: 1
Document Type: Article
ID: 669113.0
Selective Detection of Allosteric Phosphatase Inhibitors
Authors: Schneider, Ralf; Beumer, Claudia; Simard, Jeffrey R.; Grütter, Christian; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2013-05-08
Title of Journal: Journal of the American Chemical Society
Volume: 135
Issue / Number: 18
Start Page: 6838
End Page: 6841
Sequence Number of Article: 1
Document Type: Article
ID: 667307.0
Natural-product-derived fragments for fragment-based ligand discovery
Authors: Over, Björn; Wetzel, Stefan; Grütter, Christian; Nakai, Yasushi; Renner, Steffen; Rauh, Daniel; Waldmann, Herbert
Date of Publication (YYYY-MM-DD): 2013-01
Title of Journal: Nature Chemistry
Volume: 5
Issue / Number: 1
Start Page: 21
End Page: 28
Sequence Number of Article: 1
Document Type: Article
ID: 628939.0
Fluorophore Labeled Kinase Detects Ligands That Bind within the MAPK Insert of p38α Kinase
Authors: Getlik, Matthäus; Simard, Jeffrey R.; Termathe, Martin; Grütter, Christian; Rabiller, Matthias; Van Otterlo, Willem A. L.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2012-07-02
Title of Journal: PLoS ONE
Volume: 7
Issue / Number: 7
Start Page: e39713-1
End Page: e39713-10
Sequence Number of Article: 1
Document Type: Article
ID: 611213.0
Targeting GSK3 from Ustilago maydis: Type-II Kinase Inhibitors
as Potential Antifungals
Authors: Grütter, Christian; Simard, Jeffrey R.; Mayer-Wrangowski, Svenja C.; Schreier, Peter H.; Pérez-Martín, José; Richters, André; Getlik, Matthäus; Gutbrod, Oliver; Braun, Christoph A.; Beck, Michael E.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2012-04-30
Title of Journal: ACS Chemical Biology
Volume: 7
Issue / Number: 7
Start Page: 1257
End Page: 1267
Sequence Number of Article: 1
Document Type: Article
ID: 614971.0
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer
Authors: Peifer, Martin; Fernández-Cuesta, Lynnette; Sos, Martin L.; George, Julie; Seidel, Danila; Kasper, Lawryn H.; Plenker, Dennis; Leenders, Frauke; Sun, Ruping; Zander, Thomas; Menon, Roopika; Koker, Mirjam; Dahmen, Ilona; Müller, Christian; Di Cerbo, Vincenzo; Schildhaus, Hans-Ulrich; Altmüller, Janine; Baessmann, Ingelore; Becker, Christian; de Wilde, Bram; Vandesompele, Jo; Böhm, Diana; Ansén, Sascha; Gabler, Franziska; Wilkening, Ines; Heynck, Stefanie; Heuckmann, Johannes M.; Lu, Xin; Carter, Scott L.; Cibulskis, Kristian; Banerji, Shantanu; Getz, Gad; Park, Kwon-Sik; Rauh, Daniel; Grütter, Christian; Fischer, Matthias; Pasqualucci, Laura; Wright, Gavin; Wainer, Zoe; Russell, Prudence; Petersen, Iver; Chen, Yuan; Stoelben, Erich; Ludwig, Corinna; Schnabel, Philipp; Hoffmann, Hans; Muley, Thomas; Brockmann, Michael; Engel-Riedel, Walburga; Muscarella, Lucia A.; Fazio, Vito M.; Groen, Harry; Timens, Wim; Sietsma, Hannie; Thunnissen, Erik; Smit, Egbert; Heideman, Danielle A. M.; Snijders, Peter J. F.; Capuzzo, Frederico; Ligorio, Claudia; Damiani, Stefania; Field, John; Solberg, Steinar; Brustugun, Odd Terje; Lund-Iversen, Marius; Sänger, Jörg; Clement, Joachim H.; Soltermann, Alex; Moch, Holger; Weder, Walter; Solomon, Benjamin; Soria, Jean-Charles; Valldire, Pierre; Besse, Benjamin; Brambilla, Elisabeth; Brambilla, Christian; Lantuejoul, Sylvie; Lorimier, Philippe; Schneider, Peter M.; Hallek, Michael; Pao, William; Meyerson, Matthew; Sage, Julien; Shendure, Jay; Schneider, Robert; Büttner, Reinhard; Wolf, Jürgen; Nürnberg, Peter; Perner, Sven; Heukamp, Lukas C.; Brindie, Paul K.; Haas, Stefan; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2012
Title of Journal: Nature Genetics
Volume: 44
Issue / Number: 10
Start Page: 1104-
End Page: 11xx
Document Type: Article
ID: 624882.0
Identification of Ustilago maydis Aurora Kinase As a Novel Antifungal Target
Authors: Tückmantel, Sandra; Greul, Jörg N.; Janning, Petra; Brockmeyer, Andreas; Grütter, Christian; Simard, Jeffrey R.; Gutbrod, Oliver; Beck, Michael E.; Tietjen, Klaus; Rauh, Daniel; Schreier, Peter H.
Date of Publication (YYYY-MM-DD): 2011-09
Title of Journal: Asc Chemical Biology
Volume: 6
Issue / Number: 9
Start Page: 926
End Page: 933
Sequence Number of Article: 1
Document Type: Article
ID: 572728.0
Synthesis and biological evaluation of 7-substituted-1-(3-bromophenylamino)isoquinoline-4-carbonitriles
as inhibitors of myosin light chain kinase and epidermal
growth factor receptor
Authors: Rode, Haridas B.; Sos, Martin L.; Grütter, Christian; Heynck, Stefanie; Simard, Jeffrey R.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2011-01
Title of Journal: Bioorganic & Medicinal Chemistry
Volume: 19
Issue / Number: 1
Start Page: 429
End Page: 439
Sequence Number of Article: 1
Document Type: Article
ID: 535425.0
Synthesis and biological evaluation of 7-substituted-1-(3-bromophenylamino)isoquinoline-4-carbonitriles as inhibitors of myosin light chain kinase and epidermal growth factor receptor
Authors: Rode, Harras B.; Sos, Martin L.; Grütter, Christian; Heynck, Stefanie; Simard, Jeffrey R.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2011
Title of Journal: Bioorganic and Medicinal Chemistry
Volume: 19
Issue / Number: 1
Start Page: 429
End Page: 439
Document Type: Article
ID: 522174.0
ALK mutations conferring differential resistance to structurally diverse ALK inhibitors
Authors: Heuckmann, Johannes M.; Hölzel, Michael; Sos, Martin L.; Heynck, Stefanie; Balke-Want, Hyatt; Koker, Mirjam; Peifer, Martin; Weiss, Jonathan; Lovly, Christine M.; Grütter, Christian; Rauh, Daniel; Pao, William; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2011
Title of Journal: Clinical Cancer Research
Volume: 17
Issue / Number: 23
Start Page: 7394
End Page: 7401
Document Type: Article
ID: 575648.0
Entries: 1-10  
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