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Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions
Authors: Thiel, Philipp; Röglin, Lars; Meissner, Nicole; Hennig, Sven; Kohlbacher, Oliver; Ottmann, Christian
Date of Publication (YYYY-MM-DD): 2013-10-04
Title of Journal: Chemical Communication
Volume: 49
Issue / Number: 76
Start Page: 8468
End Page: 8470
Sequence Number of Article: 1
Document Type: Article
ID: 670157.0
Stabilization of Physical RAF/14-3-3 Interaction by Cotylenin A as Treatment Strategy for RAS Mutant Cancers
Authors: Molzan, Manuela; Kasper, Stefan; Röglin, Lars; Skwarczynska, Malgorzata; Sassa, Takeshi; Inoue, Takatsugu; Breitenbuecher, Frank; Ohkanda, Junko; Kato, Nobuo; Schuler, Martin; Ottmann, Christian
Date of Publication (YYYY-MM-DD): 2013-09-20
Title of Journal: ACS Chemical Biology
Volume: 8
Issue / Number: 9
Start Page: 1869
End Page: 1875
Sequence Number of Article: 1
Document Type: Article
ID: 669338.0
Preface: Inhibition and stabilization of protein-protein interactions
Authors: Ottmann, Christian; Robinson, John
Date of Publication (YYYY-MM-DD): 2013-07-15
Title of Journal: Bioorganic & Medicinal Chemistry
Volume: 21
Issue / Number: 14
Start Page: 3981
End Page: 3981
Sequence Number of Article: 1
Document Type: Article
ID: 669118.0
Interaction of 14-3-3 proteins with the Estrogen Receptor Alpha F domain provides a drug target interface
Authors: De Vries-van Leeuwen, Ingrid J.; Pereira, Daniel da Costa; Flach, Koen D.; Piersma, Sander R.; Haase, Christian; Bier, David; Yalcin, Zeliha; Michalides, Rob; Feenstra, K. Anton; Jiménez, Connie R.; de Greef, Tom F. A.; Brunsveld, Luc; Ottmann, Christian; Zwart, Wilbert; de Boer, Albertus H.
Date of Publication (YYYY-MM-DD): 2013-05-28
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 110
Issue / Number: 22
Start Page: 8894
End Page: 8899
Sequence Number of Article: 1
Document Type: Article
ID: 669243.0
A Semisynthetic Fusicoccane Stabilizes a Protein-Protein Interaction and Enhances the Expression of K+ Channels at the Cell Surface
Authors: Anders, Carolin; Higuchi, Yusuke; Koschinsky, Kristin; Bartel, Maria; Schumacher, Benjamin; Thiel, Philipp; Nitta, Hajime; Preisig-Müller, Regina; Schlichthörl, Günter; Renigunta, Vijay; Ohkanda, Junko; Daut, Jürgen; Kato, Nobuo; Ottmann, Christian
Date of Publication (YYYY-MM-DD): 2013-04-18
Title of Journal: Chemistry & Biology
Volume: 20
Issue / Number: 4
Start Page: 583
End Page: 593
Sequence Number of Article: 1
Document Type: Article
ID: 658267.0
Proline Primed Helix Length as a Modulator of the Nuclear Receptor-Coactivator Interaction
Authors: Fuchs, Sascha; Nguyen, Hoang D.; Phan, Trang T. P.; Burton, Matthew F.; Nieto, Lidia; De Vries-van Leeuwen, Ingrid J.; Schmidt, Andrea; Goodarzifard, Monireh; Agten, Stijn M.; Rose, Rolf; Ottmann, Christian; Milroy, Lech-Gustav; Brunsveld, Luc
Date of Publication (YYYY-MM-DD): 2013-03-20
Title of Journal: Journal of the American Chemical Society
Volume: 135
Issue / Number: 11
Start Page: 4364
End Page: 4371
Sequence Number of Article: 1
Document Type: Article
ID: 655798.0
Subcellular localization of full-length human myeloid leukemia factor 1 (MLF1) is independent of 14-3-3 proteins
Authors: Molzan, Manuela; Ottmann, Christian
Date of Publication (YYYY-MM-DD): 2013-03
Title of Journal: Cellular & Molecular Biology Letters
Volume: 18
Issue / Number: 1
Start Page: 137
End Page: 148
Sequence Number of Article: 1
Document Type: Article
ID: 631604.0
Molecular tweezers modulate 14-3-3 protein-protein interactions
Authors: Bier, David; Rose, Rolf; Bravo-Rodriguez, Kenny; Bartel, Maria; Ramirez-Anguita, Juan Manuel; Dutt, Som; Wilch, Constanze; Klärner, Frank-Gerrit; Sanchez-Garcia, Elsa; Schrader, Thomas; Ottmann, Christian
Date of Publication (YYYY-MM-DD): 2013-03
Title of Journal: Nature Chemistry
Volume: 5
Issue / Number: 3
Start Page: 234
End Page: 239
Sequence Number of Article: 1
Document Type: Article
ID: 655799.0
Activation of NF-κB signalling by fusicoccin-induced dimerization
Authors: Skwarczynska, Malgorzata; Molzan, Manuela; Ottmann, Christian
Date of Publication (YYYY-MM-DD): 2013-01-29
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 110
Issue / Number: 5
Start Page: E377
End Page: E386
Sequence Number of Article: 1
Document Type: Article
ID: 634997.0
Stabilization and Inhibition of Protein–Protein Interactions: The 14-3-3 Case Study
Authors: Milroy, Lech-Gustav; Brunsveld, Luc; Ottmann, Christian
Date of Publication (YYYY-MM-DD): 2013-01
Title of Journal: ACS Chemical Biology
Volume: 8
Issue / Number: 1
Start Page: 27
End Page: 35
Sequence Number of Article: 1
Document Type: Article
ID: 633590.0
Entries: 1-10  
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