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| Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions |
| Authors: Sos, Martin L.; Michel, Kathrin; Zander, Thomas; Weiss, Jonathan; Frommolt, Peter; Peifer, Martin; Li, Danan; Ullrich, Roland; Koker, Mirjam; Fischer, Florian; Shimamura, Takeshi; Rauh, Daniel; Mermel, Craig; Fischer, Stefanie; Stückrath, Isabel; Heynck, Stefanie; Beroukhim, Rameen; Lin, William; Winckler, Wendy; Shah, Kinjal; LaFramboise, Thomas; Moriarty, Whei F.; Hanna, Megan; Tolosi, Laura; Rahnenführer, Jörg; Verhaak, Roel; Chiang, Derek; Getz, Gad; Hellmich, Martin; Wolf, Jürgen; Girard, Luc; Peyton, Michael; Weir, Barbara A.; Chen, Tzu-Hsiu; Greulich, Heidi; Barretina, Jordi; Shapiro, Geoffrey I.; Garraway, Levi A.; Gazdar, Adi F.; Minna, John D.; Meyerson, Matthew; Wong, Kwok-Kin; Thomas, Roman K. | | Date of Publication (YYYY-MM-DD): 2009-06 | | Title of Journal: Journal of Clinical Investigation | | Volume: 119 | | Issue / Number: 6 | | Start Page: 1727 | | End Page: 1740 | | Document Type: Article | | ID: 424203.0 |
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| Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions |
| Authors: Sos, Martin L.; Michel, Kathrin; Zander, Thomas; Weiss, Jonathan; Frommolt, Peter; Peifer, Martin; Li, Danan; Ullrich, Roland; Koker, Mirjam; Fischer, Florian; Shimamura, Takeshi; Rauh, Daniel; Mermel, Craig; Fischer, Stefanie; Stückrath, Isabel; Heynck, Stefanie; Beroukhim, Rameen; Lin, William; Winckler, Wendy; Shah, Kinjal; LaFramboise, Thomas; Moriarty, Whei F.; Hanna, Megan; Tolosi, Laura; Rahnenführer, Jörg; Verhaak, Roel; Chiang, Derek; Getz, Gad; Hellmich, Martin; Wolf, Jürgen; Girard, Luc; Peyton, Michael; Weir, Barbara A.; Chen, Tzu-Hsiu; Greulich, Heidi; Barretina, Jordi; Shapiro, Geoffrey I.; Garraway, Levi A.; Gazdar, Adi F.; Minna, John D.; Meyerson, Matthew; Wong, Kwok-Kin; Thomas, Roman K. | | Date of Publication (YYYY-MM-DD): 2009-06 | | Title of Journal: Journal of Clinical Investigation | | Volume: 119 | | Issue / Number: 6 | | Start Page: 1727 | | End Page: 1740 | | Document Type: Article | | ID: 572965.0 |
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| Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance |
| Authors: Shimamura, Takeshi; Li, Danan; Ji, Hongbin; Haringsma, Henry J.; Liniker, Elizabeth; Borgman, Christa L.; Lowell, April M.; Minami, Yuko; McNamara, Kate; Perera, Samanthi A.; Zaghlul, Sara; Thomas, Roman K.; Greulich, Heidi; Kobayashi, Susumu; Chirieac, Lucian R.; Padera, Robert F.; Kubo, Shigeto; Takahashi, Masaya; Tenen, Daniel G.; Meyerson, Matthew; Wong, Kwok-Kin; Shapiro, Geoffrey I. | | Date of Publication (YYYY-MM-DD): 2008-07 | | Title of Journal: Cancer Research | | Volume: 68 | | Issue / Number: 14 | | Start Page: 5827 | | End Page: 5838 | | Document Type: Article | | ID: 380156.0 |
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| Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy |
| Authors: Li, Danan; Shimamura, Takeshi; Ji, Hong Bin; Chen, Liang; Haringsma, Henry J.; McNamara, Kate; Liang, Mei-Chih; Perera, Samanthi A.; Zaghlul, Sara; Borgman, Christa L.; Kubo, Shigeto; Takahashi, Masaya; Sun, Yan Ping; Chirieac, Lucian R.; Padera, Robert F.; Lindeman, Neal I.; Janni, Pase A.; Thomas, Roman K.; Meyerson, Matthew L.; Eck, Michael J.; Engelman, Jeffrey A.; Shapiro, Geoffrey I.; Wong, Kwok-Kin | | Date of Publication (YYYY-MM-DD): 2007-07 | | Title of Journal: Cancer Cell | | Volume: 12 | | Issue / Number: 1 | | Start Page: 81 | | End Page: 93 | | Document Type: Article | | ID: 376512.0 |
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| Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models |
| Authors: Ji, Hongbin; Wang, Zhenxiong; Perera, Samanthi A.; Li, Danan; Liang, Mei-Chih; Zaghlul, Sara; McNamara, Kate; Chen, Liang; Albert, Mitchell; Sun, Yanping; Al-Hashem, Ruqayyah; Chirieac, Lucian R.; Padera, Robert; Bronson, Roderick T.; Thomas, Roman K.; Garraway, Levi A.; Jänne, Pasi A.; Johnson, Bruce E.; Chin, Lynda; Wong, Kwok-Kin | | Date of Publication (YYYY-MM-DD): 2007-05-15 | | Title of Journal: Cancer Research | | Volume: 67 | | Issue / Number: 10 | | Start Page: 4933 | | End Page: 4939 | | Document Type: Article | | ID: 380158.0 |
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| Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase Iinhibitors |
| Authors: Ji, Hongbin; Zhao, Xiaojun; Yuza, Yuki; Shimamura, Takeshi; Li, Danan; Protopopov, Alexei; Jung, Boonim L.; McNamara, Kate; Xia, Huili; Glatt, Karen A.; Thomas, Roman K.; Sasaki, Hidefumi; Horner, James W.; Eck, Michael; Mitchell, Albert; Sun, Yangping; Al-Hashem, Ruqayyah; Bronson, Roderick T.; Rabindran, Sridhar K.; Discafani, Carolyn M.; Maher, Elizabeth; Shapiro, Geoffrey I.; Meyerson, Matthew; Wong, Kwok-Kin | | Date of Publication (YYYY-MM-DD): 2006-05-16 | | Title of Journal: Proceedings of the National Academy of Sciences of the United States of America | | Volume: 103 | | Issue / Number: 20 | | Start Page: 7817 | | End Page: 7822 | | Document Type: Article | | ID: 380161.0 |
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