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Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M |
Authors: Rusch, Marion; Zimmermann, Tobias J.; Bürger, Marco; Dekker, Frank J.; Görmer, Kristina; Triola, Gemma; Brockmeyer, Andreas; Janning, Petra; Böttcher, Thomas; Sieber, Stephan A.; Vetter, Ingrid R.; Hedberg, Christian; Waldmann, Herbert | Date of Publication (YYYY-MM-DD): 2011-10-10 | Title of Journal: Angewandte Chemie | Volume: 123 | Issue / Number: 42 | Start Page: 10012 | End Page: 10016 | Sequence Number of Article: 1 | Document Type: Article | ID: 573979.0 |
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Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M |
Authors: Rusch, Marion; Zimmermann, Tobias J.; Bürger, Marco; Dekker, Frank J.; Görmer, Kristina; Triola, Gemma; Brockmeyer, Andreas; Janning, Petra; Böttcher, Thomas; Sieber, Stephan A.; Vetter, Ingrid R.; Hedberg, Christian; Waldmann, Herbert | Date of Publication (YYYY-MM-DD): 2011-10-10 | Title of Journal: Angewandte Chemie International Edition | Volume: 50 | Issue / Number: 42 | Start Page: 9838 | End Page: 9842 | Sequence Number of Article: 1 | Document Type: Article | ID: 573995.0 |
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Development of Highly Potent Inhibitors of the Ras-Targeting Human Acyl Protein Thioesterases Based on Substrate Similarity Design |
Authors: Hedberg, Christian; Dekker, Frank J.; Rusch, Marion; Renner, Steffen; Wetzel, Stefan; Vartak, Nachiket; Gerding-Reimers, Claas; Bon, Robin S.; Bastiaens, Philippe I. H.; Waldmann, Herbert | Date of Publication (YYYY-MM-DD): 2011-10-10 | Title of Journal: Angewandte Chemie | Volume: 123 | Issue / Number: 42 | Start Page: 10006 | End Page: 10011 | Sequence Number of Article: 1 | Document Type: Article | ID: 574000.0 |
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Development of Highly Potent Inhibitors of the Ras-Targeting Human Acyl Protein Thioesterases Based on Substrate Similarity Design |
Authors: Hedberg, Christian; Dekker, Frank J.; Rusch, Marion; Renner, Steffen; Wetzel, Stefan; Vartak, Nachiket; Gerding-Reimers, Claas; Bon, Robin S.; Bastiaens, Philippe I. H.; Waldmann, Herbert | Date of Publication (YYYY-MM-DD): 2011-10-10 | Title of Journal: Angewandte Chemie International Edition | Volume: 50 | Issue / Number: 42 | Start Page: 9832 | End Page: 9837 | Sequence Number of Article: 1 | Document Type: Article | ID: 574004.0 |
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Small molecule inhibition of protein depalmitoylation as a new approach towards downregulation of oncogenic Ras signalling |
Authors: Dekker, Frank J.; Hedberg, Christian | Date of Publication (YYYY-MM-DD): 2011-02-15 | Title of Journal: Bioorganic & Medicinal Chemistry | Volume: 19 | Issue / Number: 4 | Start Page: 1376 | End Page: 1380 | Sequence Number of Article: 1 | Document Type: Article | ID: 547478.0 |
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Small-molecule inhibition of APT1 affects Ras localization and signaling |
Authors: Dekker, Frank J.; Rocks, Oliver; Vartak, Nachiket; Menninger, Sascha; Hedberg, Christian; Balamurugan, Rangarajan; Wetzel, Stefan; Renner, Steffen; Gerauer, Marc; Schölermann, Beate; Rusch, Marion; Kramer, John W.; Rauh, Daniel; Coates, Geoffrey W.; Brunsveld, Luc; Bastiaens, Philippe I. H.; Waldmann, Herbert | Date of Publication (YYYY-MM-DD): 2010-04 | Title of Journal: Nature Chemical Biology | Volume: 6 | Issue / Number: 6 | Start Page: 449 | End Page: 456 | Sequence Number of Article: 1 | Document Type: Article | ID: 476024.0 |
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Protein structure similarity clustering (PSSC) and natural product structure as inspiration sources for drug development and chemical genomics |
Authors: Dekker, Frank J.; Koch, Markus A.; Waldmann, Herbert | Date of Publication (YYYY-MM-DD): 2005-06 | Title of Journal: Current Opinion in Chemical Biology | Volume: 9 | Issue / Number: 3 | Start Page: 232 | End Page: 239 | Sequence Number of Article: 1 | Document Type: Article | ID: 239872.0 |
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Binding of a Diphosphorylated-ITAM Peptide to Spleen Tyrosine Kinase (Syk) Induces Distal Conformational Changes: A Hydrogen Exchange Mass Spectrometry Study |
Authors: Catalina, M. Isabel; Fischer, Marcel J. E.; Dekker, Frank J.; Liskamp, Rob M. J.; Heck, Albert J. R. | Date of Publication (YYYY-MM-DD): 2005-05-23 | Title of Journal: Journal of the American Society for Mass Spectrometry | Volume: 16 | Issue / Number: 7 | Start Page: 1039 | End Page: 1051 | Sequence Number of Article: 1 | Document Type: Article | ID: 241695.0 |
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