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Entries: 1-10  
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Inhibiting the palmitoylation/depalmitoylation cycle selectively reduces the growth of hematopoietic cells expressing oncogenic Nras
Authors: Xu, Jin; Hedberg, Christian; Dekker, Frank J.; Li, Qing; Haigis, Kevin M.; Hwang, Eugene; Waldmann, Herbert; Shannon, Kevin
Date of Publication (YYYY-MM-DD): 2012-01-26
Title of Journal: Blood
Volume: 119
Issue / Number: 4
Start Page: 1032
End Page: 1035
Sequence Number of Article: 1
Document Type: Article
ID: 581715.0
 
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Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M
Authors: Rusch, Marion; Zimmermann, Tobias J.; Bürger, Marco; Dekker, Frank J.; Görmer, Kristina; Triola, Gemma; Brockmeyer, Andreas; Janning, Petra; Böttcher, Thomas; Sieber, Stephan A.; Vetter, Ingrid R.; Hedberg, Christian; Waldmann, Herbert
Date of Publication (YYYY-MM-DD): 2011-10-10
Title of Journal: Angewandte Chemie
Volume: 123
Issue / Number: 42
Start Page: 10012
End Page: 10016
Sequence Number of Article: 1
Document Type: Article
ID: 573979.0
Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M
Authors: Rusch, Marion; Zimmermann, Tobias J.; Bürger, Marco; Dekker, Frank J.; Görmer, Kristina; Triola, Gemma; Brockmeyer, Andreas; Janning, Petra; Böttcher, Thomas; Sieber, Stephan A.; Vetter, Ingrid R.; Hedberg, Christian; Waldmann, Herbert
Date of Publication (YYYY-MM-DD): 2011-10-10
Title of Journal: Angewandte Chemie International Edition
Volume: 50
Issue / Number: 42
Start Page: 9838
End Page: 9842
Sequence Number of Article: 1
Document Type: Article
ID: 573995.0
Development of Highly Potent Inhibitors of the Ras-Targeting Human Acyl Protein Thioesterases Based on Substrate Similarity Design
Authors: Hedberg, Christian; Dekker, Frank J.; Rusch, Marion; Renner, Steffen; Wetzel, Stefan; Vartak, Nachiket; Gerding-Reimers, Claas; Bon, Robin S.; Bastiaens, Philippe I. H.; Waldmann, Herbert
Date of Publication (YYYY-MM-DD): 2011-10-10
Title of Journal: Angewandte Chemie
Volume: 123
Issue / Number: 42
Start Page: 10006
End Page: 10011
Sequence Number of Article: 1
Document Type: Article
ID: 574000.0
Development of Highly Potent Inhibitors of the Ras-Targeting Human Acyl Protein Thioesterases Based on Substrate Similarity Design
Authors: Hedberg, Christian; Dekker, Frank J.; Rusch, Marion; Renner, Steffen; Wetzel, Stefan; Vartak, Nachiket; Gerding-Reimers, Claas; Bon, Robin S.; Bastiaens, Philippe I. H.; Waldmann, Herbert
Date of Publication (YYYY-MM-DD): 2011-10-10
Title of Journal: Angewandte Chemie International Edition
Volume: 50
Issue / Number: 42
Start Page: 9832
End Page: 9837
Sequence Number of Article: 1
Document Type: Article
ID: 574004.0
Raft Protein Clustering Alters N-Ras Membrane Interactions and Activation Pattern
Authors: Eisenberg, Sharon; Beckett, Alison J.; Prior, Ian A.; Dekker, Frank J.; Hedberg, Christian; Waldmann, Herbert; Ehrlich, Marcelo; Henis, Yoav I.
Date of Publication (YYYY-MM-DD): 2011-10
Title of Journal: Molecular and Cellular Biology
Volume: 31
Issue / Number: 19
Start Page: 3938
End Page: 3952
Sequence Number of Article: 1
Document Type: Article
ID: 572119.0
Small molecule inhibition of protein depalmitoylation as a new approach towards downregulation of oncogenic Ras signalling
Authors: Dekker, Frank J.; Hedberg, Christian
Date of Publication (YYYY-MM-DD): 2011-02-15
Title of Journal: Bioorganic & Medicinal Chemistry
Volume: 19
Issue / Number: 4
Start Page: 1376
End Page: 1380
Sequence Number of Article: 1
Document Type: Article
ID: 547478.0
Small-molecule inhibition of APT1 affects Ras localization and signaling
Authors: Dekker, Frank J.; Rocks, Oliver; Vartak, Nachiket; Menninger, Sascha; Hedberg, Christian; Balamurugan, Rangarajan; Wetzel, Stefan; Renner, Steffen; Gerauer, Marc; Schölermann, Beate; Rusch, Marion; Kramer, John W.; Rauh, Daniel; Coates, Geoffrey W.; Brunsveld, Luc; Bastiaens, Philippe I. H.; Waldmann, Herbert
Date of Publication (YYYY-MM-DD): 2010-04
Title of Journal: Nature Chemical Biology
Volume: 6
Issue / Number: 6
Start Page: 449
End Page: 456
Sequence Number of Article: 1
Document Type: Article
ID: 476024.0
Protein structure similarity clustering (PSSC) and natural product structure as inspiration sources for drug development and chemical genomics
Authors: Dekker, Frank J.; Koch, Markus A.; Waldmann, Herbert
Date of Publication (YYYY-MM-DD): 2005-06
Title of Journal: Current Opinion in Chemical Biology
Volume: 9
Issue / Number: 3
Start Page: 232
End Page: 239
Sequence Number of Article: 1
Document Type: Article
ID: 239872.0
Binding of a Diphosphorylated-ITAM Peptide to Spleen Tyrosine Kinase (Syk) Induces Distal Conformational Changes: A Hydrogen Exchange Mass Spectrometry Study
Authors: Catalina, M. Isabel; Fischer, Marcel J. E.; Dekker, Frank J.; Liskamp, Rob M. J.; Heck, Albert J. R.
Date of Publication (YYYY-MM-DD): 2005-05-23
Title of Journal: Journal of the American Society for Mass Spectrometry
Volume: 16
Issue / Number: 7
Start Page: 1039
End Page: 1051
Sequence Number of Article: 1
Document Type: Article
ID: 241695.0
Entries: 1-10  
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