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Entries: 1-10  
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Enabling Large-Scale Design, Synthesis and Validation of Small Molecule Protein-Protein Antagonists
Authors: Koes, D.; Khoury, K.; Huang, Y. J.; Wang, W.; Bista, M.; Popowicz, G. M.; Wolf, S.; Holak, T. A.; Domling, A.; Camacho, C. J.
Date of Publication (YYYY-MM-DD): 2012-03-12
Title of Journal: PLoS ONE
Volume: 7
Issue / Number: 3
Start Page: [1]
End Page: [8]
Sequence Number of Article: e32839
Document Type: Article
ID: 609523.0
 
Full text / Content available
Structure of the Stapled p53 Peptide Bound to Mdm2
Authors: Baek, S.; Kutchukian, P. S.; Verdine, G. L.; Huber, R.; Holak, T. A.; Lee, K. W.; Popowicz, G. M.
Date of Publication (YYYY-MM-DD): 2012-01-11
Title of Journal: Journal of the American Chemical Society
Volume: 134
Issue / Number: 1
Start Page: 103
End Page: 106
Document Type: Article
ID: 608876.0
Exhaustive Fluorine Scanning toward Potent p53-Mdm2 Antagonists
Authors: Huang, Y. J.; Wolf, S.; Koes, D.; Popowicz, G. M.; Camacho, C. J.; Holak, T. A.; Domling, A.
Date of Publication (YYYY-MM-DD): 2012-01-02
Title of Journal: ChemMedChem
Volume: 7
Issue / Number: 1
Start Page: 49
End Page: 52
Document Type: Article
ID: 596811.0
Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing
Authors: Mishra, S. K.; Ammon, T.; Popowicz, G. M.; Krajewski, M.; Nagel, R. J.; Ares, M.; Holak, T. A.; Jentsch, S.
Date of Publication (YYYY-MM-DD): 2011-06-09
Title of Journal: Nature
Volume: 474
Issue / Number: 7350
Start Page: 173
End Page: 178
Document Type: Article
ID: 569830.0
The p53-MDM2/MDMX axis - A chemotype perspective
Authors: Khoury, K.; Popowicz, G. M.; Holak, T. A.; Domling, A.
Date of Publication (YYYY-MM-DD): 2011-04
Title of Journal: Medchemcomm
Volume: 2
Issue / Number: 4
Start Page: 246
End Page: 260
Document Type: Article
ID: 569827.0
The Structure-Based Design of Mdm2/Mdmx-p53 Inhibitors Gets Serious
Authors: Popowicz, G. M.; Domling, A.; Holak, T. A.
Date of Publication (YYYY-MM-DD): 2011
Title of Journal: Angewandte Chemie-International Edition
Volume: 50
Issue / Number: 12
Start Page: 2680
End Page: 2688
Document Type: Article
ID: 561332.0
Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation
Authors: Ducka, A. M.; Joel, P.; Popowicz, G. M.; Trybus, K. M.; Schleicher, M.; Noegel, A. A.; Huber, R.; Holak, T. A.; Sitar, T.
Date of Publication (YYYY-MM-DD): 2010-06-29
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 107
Issue / Number: 26
Start Page: 11757
End Page: 11762
Document Type: Article
ID: 479871.0
Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery
Authors: Popowicz, G. M.; Czarna, A.; Wolf, S.; Wang, K.; Wang, W.; Domling, A.; Holak, T. A.
Date of Publication (YYYY-MM-DD): 2010-03-15
Title of Journal: Cell Cycle
Volume: 9
Issue / Number: 6
Start Page: 1104
End Page: 1111
Document Type: Article
ID: 475428.0
Robust Generation of Lead Compounds for Protein-Protein Interactions by Computational and MCR Chemistry: p53/Hdm2 Antagonists
Authors: Czarna, A.; Beck, B.; Srivastava, S.; Popowicz, G. M.; Wolf, S.; Huang, Y. J.; Bista, M.; Holak, T. A.; Domling, A.
Date of Publication (YYYY-MM-DD): 2010
Title of Journal: Angewandte Chemie-International Edition
Volume: 49
Issue / Number: 31
Start Page: 5352
End Page: 5356
Document Type: Article
ID: 493364.0
Structures of the Arm-type Binding Domains of HPI and HAI7 Integrases
Authors: Szwagierczak, A.; Antonenka, U.; Popowicz, G. M.; Sitar, T.; Holak, T. A.; Rakin, A.
Date of Publication (YYYY-MM-DD): 2009-11-13
Title of Journal: Journal of Biological Chemistry
Volume: 284
Issue / Number: 46
Start Page: 31664
End Page: 31671
Document Type: Article
ID: 439549.0
Entries: 1-10  
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