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Entries: 1-8  
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Large-format, high-speed, X-ray pnCCDs combined with electron and ion imaging spectrometers in a multipurpose chamber for experiments at 4th generation light sources.
Authors: Strueder, L.; Epp, S.; Rolles, D.; Hartmann, R.; Holl, P.; Lutz, G.; Soltau, H.; Eckart, R.; Reich, C.; Heinzinger, K.; Thamm, C.; Rudenko, A.; Krasniqi, F.; Kuehnel, K. U.; Bauer, C.; Schroeter, C. D.; Moshammer, R.; Techert, S.; Miessner, D.; Porro, M.; Haelker, O.; Meidinger, N.; Kimmel, N.; Andritschke, R.; Schopper, F.; Weidenspointer, G.; Ziegler, A.; Pietschner, D.; Herrmann, S.; Pietsch, U.; Walenta, A.; Leitenberger, W.; Bostedt, C.; Moeller, T.; Rupp, D.; Adolph, M.; Graafsma, H.; Hirsemann, H.; Gaertner, K.; Richter, R.; Foucar, L.; Shoeman, R. L.; Schlichting, I.; Ullrich, J.
Date of Publication (YYYY-MM-DD): 2010-03-11
Title of Journal: Nuclear Instruments and Methods in Physics Research A
Volume: 614
Issue / Number: 3
Start Page: 483
End Page: 496
Document Type: Article
ID: 463788.0
Large-format, high-speed, X-ray pnCCDs combined with electron and ion imaging spectrometers in a multipurpose chamber for experiments at 4th generation light sources
Authors: Strüder, L.; Epp, S.; Rolles, D.; Hartmann, R.; Holl, P.; Lutz, G.; Soltau, H.; Eckart, R.; Reich, C.; Heinzinger, K.; Thamm, C.; Rudenko, A.; Krasniqi, F.; Kühnel, K. U.; Bauer, C.; Schröter, C. D.; Moshammer, R.; Techert, S.; Miessner, D.; Porro, M.; Haelker, O.; Meidinger, N.; Kimmel, N.; Andritschke, R.; Schopper, F.; Weidenspointer, G.; Ziegler, A.; Pietschner, D.; Herrmann, S.; Pietsch, U.; Walenta, A.; Leitenberger, W.; Bostedt, C.; Moeller, T.; Rupp, D.; Adolph, M.; Graafsma, H.; Hirsemann, H.; Gärtner, K.; Richter, R.; Foucar, L.; Shoeman, R. L.; Schlichting, I.; Ullrich, J.
Date of Publication (YYYY-MM-DD): 2010-03-11
Title of Journal: Nuclear Instruments and Methods in Physics Research Section A
Volume: 614
Issue / Number: 3
Start Page: 483
End Page: 496
Document Type: Article
ID: 498872.0
Potentiating AZT activation: Structure of wild-type and mutant human thymidylate kinase suggest reasons for the mutants' improved kinetics with the HIV prodrug metabolite AZTMP.
Authors: Ostermann, N.; Lavie, A.; Padiyar, S.; Brundiers, R.; Veit, T.; Reinstein, J.; Goody, R. S.; Konrad, M.; Schlichting, I.
Date of Publication (YYYY-MM-DD): 2000
Title of Journal: Journal of Molecular Biology
Volume: 304
Start Page: 43
End Page: 53
Document Type: Article
ID: 233448.0
Insights into the phosphoryltransfer mechanism of human thymidylate kinase gained from crystal structures of enzyme complexes along the reaction coordinate.
Authors: Ostermann, N.; Schlichting, I.; Brundiers, R.; Konrad, M.; Reinstein, J.; Veit, T.; Goody, R. S.; Lavie, A.
Date of Publication (YYYY-MM-DD): 2000
Title of Journal: Structure
Volume: 8
Start Page: 629
End Page: 642
Document Type: Article
ID: 233449.0
Modifying human thymidylate kinase to potentiate AZT activation.
Authors: Brundiers, R.; Lavie, A.; Veit, T.; Reinstein, J.; Schlichting, I.; Ostermann, N.; Goody, R. S.; Konrad, M.
Date of Publication (YYYY-MM-DD): 1999
Title of Journal: Journal of Biological Chemistry
Volume: 274
Start Page: 35289
End Page: 35292
Document Type: Article
ID: 223405.0
Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor P1-(5′-adenosyl)P5-(5′-thymidyl) pentaphosphate (TP5A) at 2.0 Å resolution: Implications for catalysis and AZT activation.
Authors: Lavie, A.; Konrad, M.; Brundiers, R.; Goody, R. S.; Schlichting, I.; Reinstein, J.
Date of Publication (YYYY-MM-DD): 1998
Title of Journal: Biochemistry
Volume: 37
Start Page: 3677
End Page: 3686
Document Type: Article
ID: 228769.0
Structural basis for efficient phosphorylation of 3′-azidothymidine monophosphate by Escherichia coli thymidylate kinase.
Authors: Lavie, A.; Ostermann, N.; Brundiers, R.; Goody, R. S.; Reinstein, J.; Konrad, M.; Schlichting, I.
Date of Publication (YYYY-MM-DD): 1998
Title of Journal: Proceedings of the National Academy of Sciences USA
Volume: 95
Start Page: 14045
End Page: 14050
Document Type: Article
ID: 228771.0
The bottleneck in AZT activation
Authors: Lavie, A.; Schlichting, I.; Vetter, I. R.; Konrad, M.; Reinstein, J.; Goody, R. S.
Date of Publication (YYYY-MM-DD): 1997-08
Title of Journal: Nature Medicine
Volume: 3
Issue / Number: 8
Start Page: 922
End Page: 924
Document Type: Article
ID: 261453.0
Entries: 1-8  
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