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Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1
Authors: Ohashi, Kadaoki; Sequist, Lecia V.; Moran, Teresa; Chmielecki, Juliann; Lin, Ya-Lun; Pan, Yumei; Wang, Lu; de Stanchina, Elisa; Shien, Kazuhiko; Aoe, Keisuke; Toyooka, Shinichi; Kiura, Katsuyuki; Fernandez-Cuesta, Lynnette; Fidias, Panos; Yang, James Chih-Hsin; Miller, Vincent A.; Riely, Gregory J.; Kris, Mark G.; Engelman, Jeffrey A.; Vnencak-Jones, Xindy L.; Dias-Santagata, Dora; Ladanyi, Marc; Pao, William
Date of Publication (YYYY-MM-DD): 2012
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 109
Issue / Number: 31
Start Page: E2127
End Page: E2133
Document Type: Article
ID: 614866.0
EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer
Authors: Koivunen, Jussi P.; Mermel, Craig; Zejnullahu, Kreshnik; Murphy, Carly; Lifshits, Eugene; Holmes, Alison J.; Choi, Hwan Geun; Kim, Jhingook; Chiang, Derek; Thomas, Roman; Lee, Jinseon; Richards, William G.; Sugarbaker, David J.; Ducko, Christopher; Lindeman, Neal; Marcoux, J. Paul; Engelman, Jeffrey A.; Gray, Nathanael S.; Lee, Charles; Meyerson, Matthew; Jänne, Pasi A.
Date of Publication (YYYY-MM-DD): 2008-07
Title of Journal: Clinical Cancer Research
Volume: 14
Issue / Number: 13
Start Page: 4275
End Page: 4283
Document Type: Article
ID: 380153.0
Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy
Authors: Li, Danan; Shimamura, Takeshi; Ji, Hong Bin; Chen, Liang; Haringsma, Henry J.; McNamara, Kate; Liang, Mei-Chih; Perera, Samanthi A.; Zaghlul, Sara; Borgman, Christa L.; Kubo, Shigeto; Takahashi, Masaya; Sun, Yan Ping; Chirieac, Lucian R.; Padera, Robert F.; Lindeman, Neal I.; Janni, Pase A.; Thomas, Roman K.; Meyerson, Matthew L.; Eck, Michael J.; Engelman, Jeffrey A.; Shapiro, Geoffrey I.; Wong, Kwok-Kin
Date of Publication (YYYY-MM-DD): 2007-07
Title of Journal: Cancer Cell
Volume: 12
Issue / Number: 1
Start Page: 81
End Page: 93
Document Type: Article
ID: 376512.0
Entries: 1-3  
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