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Entries: 1-10  
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Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer
Authors: Hammerman, Peter S.; Sos, Martin L.; Ramos, Alex H.; Xu, Chunxiao; Dutt, Amit; Zhou, Wenjun; Brace, Lear E.; Woods, Brittany A.; Lin, Wenchu; Zhang, Jianming; Deng, Xianming; Lim, San Ming; Heynck, Stefanie; Peifer, Martin; Simard, Jeffrey R.; Lawrence, Michael S.; Onofrio, Robert C.; Salvesen, Helga B.; Seidel, Danila; Zander, Thomas; Heuckmann, Johannes M.; Soltermann, Alex; Moch, Holger; Koker, Mirjam; Leenders, Frauke; Gabler, Franziska; Querings, Silvia; Ansen, Sascha; Brambilla, Elisabeth; Brambilla, Christian; Lorimier, Philippe; Brustugun, Odd Terje; Helland, Aslaug; Petersen, Iver; Clement, Joachim H.; Groen, Harry; Timens, Wim; Sietsma, Hannie; Stoelben, Erich; Wolf, Jürgen; Beer, David G.; Tsao, Ming Sound; Hanna, Megan; Hatton, Charles; Eck, Michael J.; Janne, Pasi A.; Johnson, Bruce E.; Winckler, Wendy; Greulich, Heidi; Bass, Adam J.; Cho, Jeonghee; Rauh, Daniel; Gray, Nathanael S.; Wong, Kwok-Kin; Haura, Eric B.; Thomas, Roman K.; Meyerson, Matthew
Date of Publication (YYYY-MM-DD): 2011
Title of Journal: Cancer Discovery
Volume: 1
Issue / Number: 1
Start Page: 78
End Page: 89
Document Type: Article
ID: 589439.0
Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer
Authors: Sos, Martin L.; Fischer, Stefanie; Ullrich, Roland; Peifer, Martin; Heuckmann, Johannes M.; Koker, Mirjam; Heynck, Stefanie; Stueckrath, Isabel; Weiss, Jonathan; Fischer, Florian; Michel, Kathrin; Goel, Aviva; Regales, Lucia; Politi, Katerina A.; Perera, Samanthi; Getlik, Matthaeus; Heukamp, Lukas C.; Ansen, Sascha; Zander, Thomas; Beroukhim, Rameen; Kashkar, Hamid; Shokat, Kevan M.; Sellers, William R.; Rauh, Daniel; Orr, Christine; Hoeflich, Klaus P.; Friedman, Lori; Wong, Kwok-Kin; Pao, William; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2009-10-27
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 106
Start Page: 18351
End Page: 18356
Document Type: Article
ID: 436187.0
Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer
Authors: Sos, Martin L.; Fischer, Stefanie; Ullrich, Roland; Peifer, Martin; Heuckmann, Johannes M.; Koker, Mirjam; Heynck, Stefanie; Stückrath, Isabel; Weiss, Jonathan; Fischer, Florian; Michel, Kathrin; Goel, Aviva; Regales, Lucia; Politi, Katerina A.; Perera, Samanthi; Getlik, Matthäus; Heukamp, Lukas C.; Ansén, Sascha; Zander, Thomas; Beroukhim, Rameen; Kashkar, Hamid; Shokat, Kevan M.; Sellers, William R.; Rauh, Daniel; Orr, Christine; Hoeflich, Klaus P.; Friedman, Lori; Wong, Kwok-Kin; Pao, William; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2009-10-27
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 106
Issue / Number: 43
Start Page: 18351
End Page: 18356
Sequence Number of Article: 1
Document Type: Article
ID: 439182.0
Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer
Authors: Sos, Martin L.; Fischer, Stefanie; Ullrich, Roland; Peifer, Martin; Heuckmann, Johannes M.; Koker, Mirjam; Heynck, Stefanie; Stueckrath, Isabel; Weiss, Jonathan; Fischer, Florian; Michel, Kathrin; Goel, Aviva; Regales, Lucia; Politi, Katerina A.; Perera, Samanthi; Getlik, Matthaeus; Heukamp, Lukas C.; Ansen, Sascha; Zander, Thomas; Beroukhim, Rameen; Kashkar, Hamid; Shokat, Kevan M.; Sellers, William R.; Rauh, Daniel; Orr, Christine; Hoeflich, Klaus P.; Friedman, Lori; Wong, Kwok-Kin; Pao, William; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2009-10-27
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 106
Start Page: 18351
End Page: 18356
Document Type: Article
ID: 439375.0
Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer
Authors: Sos, Martin L.; Fischer, Stefanie; Ullrich, Roland; Peifer, Martin; Heuckmann, Johannes M.; Koker, Mirjam; Heynck, Stefanie; Stueckrath, Isabel; Weiss, Jonathan; Fischer, Florian; Michel, Kathrin; Goel, Aviva; Regales, Lucia; Politi, Katerina A.; Perera, Samanthi; Getlik, Matthaeus; Heukamp, Lukas C.; Ansen, Sascha; Zander, Thomas; Beroukhim, Rameen; Kashkar, Hamid; Shokat, Kevan M.; Sellers, William R.; Rauh, Daniel; Orr, Christine; Hoeflich, Klaus P.; Friedman, Lori; Wong, Kwok-Kin; Pao, William; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2009-10-27
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 106
Start Page: 18351
End Page: 18356
Document Type: Article
ID: 572957.0
Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
Authors: Sos, Martin L.; Michel, Kathrin; Zander, Thomas; Weiss, Jonathan; Frommolt, Peter; Peifer, Martin; Li, Danan; Ullrich, Roland; Koker, Mirjam; Fischer, Florian; Shimamura, Takeshi; Rauh, Daniel; Mermel, Craig; Fischer, Stefanie; Stückrath, Isabel; Heynck, Stefanie; Beroukhim, Rameen; Lin, William; Winckler, Wendy; Shah, Kinjal; LaFramboise, Thomas; Moriarty, Whei F.; Hanna, Megan; Tolosi, Laura; Rahnenführer, Jörg; Verhaak, Roel; Chiang, Derek; Getz, Gad; Hellmich, Martin; Wolf, Jürgen; Girard, Luc; Peyton, Michael; Weir, Barbara A.; Chen, Tzu-Hsiu; Greulich, Heidi; Barretina, Jordi; Shapiro, Geoffrey I.; Garraway, Levi A.; Gazdar, Adi F.; Minna, John D.; Meyerson, Matthew; Wong, Kwok-Kin; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2009-06
Title of Journal: Journal of Clinical Investigation
Volume: 119
Issue / Number: 6
Start Page: 1727
End Page: 1740
Document Type: Article
ID: 424203.0
Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
Authors: Sos, Martin L.; Michel, Kathrin; Zander, Thomas; Weiss, Jonathan; Frommolt, Peter; Peifer, Martin; Li, Danan; Ullrich, Roland; Koker, Mirjam; Fischer, Florian; Shimamura, Takeshi; Rauh, Daniel; Mermel, Craig; Fischer, Stefanie; Stückrath, Isabel; Heynck, Stefanie; Beroukhim, Rameen; Lin, William; Winckler, Wendy; Shah, Kinjal; LaFramboise, Thomas; Moriarty, Whei F.; Hanna, Megan; Tolosi, Laura; Rahnenführer, Jörg; Verhaak, Roel; Chiang, Derek; Getz, Gad; Hellmich, Martin; Wolf, Jürgen; Girard, Luc; Peyton, Michael; Weir, Barbara A.; Chen, Tzu-Hsiu; Greulich, Heidi; Barretina, Jordi; Shapiro, Geoffrey I.; Garraway, Levi A.; Gazdar, Adi F.; Minna, John D.; Meyerson, Matthew; Wong, Kwok-Kin; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2009-06
Title of Journal: Journal of Clinical Investigation
Volume: 119
Issue / Number: 6
Start Page: 1727
End Page: 1740
Document Type: Article
ID: 572965.0
Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance
Authors: Shimamura, Takeshi; Li, Danan; Ji, Hongbin; Haringsma, Henry J.; Liniker, Elizabeth; Borgman, Christa L.; Lowell, April M.; Minami, Yuko; McNamara, Kate; Perera, Samanthi A.; Zaghlul, Sara; Thomas, Roman K.; Greulich, Heidi; Kobayashi, Susumu; Chirieac, Lucian R.; Padera, Robert F.; Kubo, Shigeto; Takahashi, Masaya; Tenen, Daniel G.; Meyerson, Matthew; Wong, Kwok-Kin; Shapiro, Geoffrey I.
Date of Publication (YYYY-MM-DD): 2008-07
Title of Journal: Cancer Research
Volume: 68
Issue / Number: 14
Start Page: 5827
End Page: 5838
Document Type: Article
ID: 380156.0
The major lung cancer-derived mutants of ERBB2 are oncogenic and are associated with sensitivity to the irreversible EGFR/ ERBB2 inhibitor HKI-272.
Authors: Minami, Y.; Shimamura, T.; Shah, Kinjal; Laframboise, Thomas; Glatt, Karen A.; Liniker, E.; Borgman, C.L.; Haringsma, H.J.; Feng, W.; Weir, B.A.; Lowell, A.M.; Lee, J. C.; Wolf, Jürgen; Shapiro, G.I.; Wong, Kwok-Kin; Meyerson, Matthew; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2007-07-26
Title of Journal: Oncogene
Volume: 26
Issue / Number: 34
Start Page: 5023
End Page: 5027
Document Type: Article
ID: 376406.0
Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy
Authors: Li, Danan; Shimamura, Takeshi; Ji, Hong Bin; Chen, Liang; Haringsma, Henry J.; McNamara, Kate; Liang, Mei-Chih; Perera, Samanthi A.; Zaghlul, Sara; Borgman, Christa L.; Kubo, Shigeto; Takahashi, Masaya; Sun, Yan Ping; Chirieac, Lucian R.; Padera, Robert F.; Lindeman, Neal I.; Janni, Pase A.; Thomas, Roman K.; Meyerson, Matthew L.; Eck, Michael J.; Engelman, Jeffrey A.; Shapiro, Geoffrey I.; Wong, Kwok-Kin
Date of Publication (YYYY-MM-DD): 2007-07
Title of Journal: Cancer Cell
Volume: 12
Issue / Number: 1
Start Page: 81
End Page: 93
Document Type: Article
ID: 376512.0
Entries: 1-10  
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