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Isoquinolin-1-one inhibitors of the MDM2-p53 interaction |
Authors: Rothweiler, U.; Czarna, A.; Krajewski, M.; Ciombor, J.; Kalinski, C.; Khazak, V.; Ross, G.; Skobeleva, N.; Weber, L.; Holak, T. A. | Date of Publication (YYYY-MM-DD): 2008-07 | Title of Journal: ChemMedChem | Volume: 3 | Issue / Number: 7 | Start Page: 1118 | End Page: 1128 | Document Type: Article | ID: 372249.0 |
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An NMR-Based antagonist induced dissociation assay for targeting the ligand-protein and protein-protein interactions in competition binding experiments |
Authors: Krajewski, M.; Rothweiler, U.; D'Silva, L.; Majumdar, S.; Klein, C.; Holak, T. A. | Date of Publication (YYYY-MM-DD): 2007-09-06 | Title of Journal: Journal of Medicinal Chemistry | Volume: 50 | Issue / Number: 18 | Start Page: 4382 | End Page: 4387 | Document Type: Article | ID: 328373.0 |
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Structural ramification for acetyl-lysine recognition by the bromodomain of human BRG1 protein, a central ATPase of the SWI/SNF remodeling complex |
Authors: Singh, M.; Popowicz, G. M.; Krajewski, M.; Holak, T. A. | Date of Publication (YYYY-MM-DD): 2007-07-23 | Title of Journal: ChemBioChem | Volume: 8 | Issue / Number: 11 | Start Page: 1308 | End Page: 1316 | Document Type: Article | ID: 328424.0 |
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Molecular determinants for the complex formation between the retinoblastoma protein and LXCXE sequences |
Authors: Singh, M.; Krajewski, M.; Mikolajka, A.; Holak, T. A. | Date of Publication (YYYY-MM-DD): 2005-11-11 | Title of Journal: Journal of Biological Chemistry | Volume: 280 | Issue / Number: 45 | Start Page: 37868 | End Page: 37876 | Document Type: Article | ID: 261720.0 |
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NMR indicates that the small molecule RITA does not block p53-MDM2 binding in vitro |
Authors: Krajewski, M.; Ozdowy, P.; D'Silva, L.; Rothweiler, U.; Holak, T. A. | Date of Publication (YYYY-MM-DD): 2005-11 | Title of Journal: Nature Medicine | Volume: 11 | Issue / Number: 11 | Start Page: 1135 | End Page: 1136 | Document Type: Article | ID: 261739.0 |
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Monitoring the effects of antagonists on protein-protein interactions with NMR spectroscopy |
Authors: D'Silva, L.; Ozdowy, P.; Krajewski, M.; Rothweiler, U.; Singh, M.; Holak, T. A. | Date of Publication (YYYY-MM-DD): 2005-09-28 | Title of Journal: Journal of the American Chemical Society | Volume: 127 | Issue / Number: 38 | Start Page: 13220 | End Page: 13226 | Document Type: Article | ID: 261723.0 |
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NMR and mass spectrometry studies of putative interactions of cell cycle proteins pRb and CDK6 with cell differentiation proteins MyoD and ID-2 |
Authors: Smialowski, P.; Singh, M.; Mikolajka, A.; Majumdar, S.; Joy, J. K.; Nalabothula, N.; Krajewski, M.; Degenkolbe, R.; Bernard, H. U.; Holak, T. A. | Date of Publication (YYYY-MM-DD): 2005-06-15 | Title of Journal: Biochimica et Biophysica Acta-Proteins and Proteomics | Volume: 1750 | Issue / Number: 1 | Start Page: 48 | End Page: 60 | Document Type: Article | ID: 261738.0 |
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