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A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity
Authors: Bramsen, Jesper B.; Laursen, Maria B.; Nielsen, Anne F.; Hansen, Thomas B.; Bus, Claus; Langkjaer, Niels; Babu, B. Ravindra; Hojland, Torben; Abramov, Mikhail; Van Aerschot, Arthur; Odadzic, Dalibor; Smicius, Romualdas; Haas, Jens; Andree, Cordula; Barman, Jharna; Wenska, Malgorzata; Srivastava, Puneet; Zhou, Chuanzheng; Honcharenko, Dmytro; Hess, Simone; Müller, Elke; Bobkov, Georgii V.; Mikhailov, Sergey N.; Fava, Eugenio; Meyer, Thomas F.; Chattopadhyaya, Jyoti; Zerial, Marino; Engels, Joachim W.; Herdewijn, Piet; Wengel, Jesper; Kjems, Jorgen
Date of Publication (YYYY-MM-DD): 2009-05
Title of Journal: Nucleic Acids Research
Volume: 37
Issue / Number: 9
Start Page: 2867
End Page: 2881
Document Type: Article
ID: 436554.0
 
Full text / Content available
A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity
Authors: Bramsen, Jesper B.; Laursen, Maria B.; Nielsen, Anne F.; Hansen, Thomas B.; Bus, Claus; Langkjær, Niels; Babu, B. Ravindra; Højland, Torben; Abramov, Mikhail; Aerschot, Arthur Van; Odadzic, Dalibor; Smicius, Romualdas; Haas, Jens; Andree, Cordula; Barman, Jharna; Wenska, Malgorzata; Srivastava, Puneet; Zhou, Chuanzheng; Honcharenko, Dmytro; Hess, Simone; Müller, Elke; Bobkov, Georgii V.; Mikhailov, Sergey N.; Fava, Eugenio; Meyer, Thomas F.; Chattopadhyaya, Jyoti; Zerial, Marino; Engels, Joachim W.; Herdewijn, Piet; Wengel, Jesper; Kjems, Jørgen
Date of Publication (YYYY-MM-DD): 2009
Title of Journal: Nucleic Acids Research
Volume: 37
Issue / Number: 9
Start Page: 2867
End Page: 2881
Document Type: Article
ID: 463164.0
Entries: 1-2  
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