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Entries: 1-10  
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Phthalazinone Pyrazoles as Potent, Selective, and Orally Bioavailable Inhibitors of Aurora-A Kinase
Authors: Prime, M. E.; Courtney, S. M.; Brookfield, F. A.; Marston, R. W.; Walker, V.; Warne, J.; Boyd, A. E.; Kairies, N. A.; von der Saal, W.; Limberg, A.; Georges, G.; Engh, R. A.; Goller, B.; Rueger, P.; Rueth, M.
Date of Publication (YYYY-MM-DD): 2011-01-13
Title of Journal: Journal of Medicinal Chemistry
Volume: 54
Issue / Number: 1
Start Page: 312
End Page: 319
Document Type: Article
ID: 556487.0
Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity
Authors: Bonn, S.; Herrero, S.; Breitenlechner, C. B.; Erlbruch, A.; Lehmann, W.; Engh, R. A.; Gassel, M.; Bossemeyer, D.
Date of Publication (YYYY-MM-DD): 2006-08-25
Title of Journal: Journal of Biological Chemistry
Volume: 281
Issue / Number: 34
Start Page: 24818
End Page: 24830
Document Type: Article
ID: 287818.0
Crystal structures of active Src kinase domain complexes
Authors: Breitenlechner, C. B.; Kairies, N. A.; Honold, K.; Scheiblich, S.; Koll, H.; Greiter, E.; Koch, S.; Schafer, W.; Huber, R.; Engh, R. A.
Date of Publication (YYYY-MM-DD): 2005-10-21
Title of Journal: Journal of Molecular Biology
Volume: 353
Issue / Number: 2
Start Page: 222
End Page: 231
Document Type: Article
ID: 256276.0
The 1.1 angstrom resolution crystal structure of the p130cas SH3 domain and ramifications for ligand selectivity
Authors: Wisniewska, M.; Bossenmaier, B.; Georges, G.; Hesse, F.; Dangl, M.; Kunkele, K. P.; Ioannidis, I.; Huber, R.; Engh, R. A.
Date of Publication (YYYY-MM-DD): 2005-04-15
Title of Journal: Journal of Molecular Biology
Volume: 347
Issue / Number: 5
Start Page: 1005
End Page: 1014
Document Type: Article
ID: 265472.0
Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase a and mutants
Authors: Breitenlechner, C. B.; Friebe, W. G.; Brunet, E.; Guido, W.; Graul, M.; Thomas, U.; Kunkele, K. P.; Schafer, W.; Gassel, M.; Bosseineyer, D.; Huber, R.; Engh, R. A.; Masjost, B.
Date of Publication (YYYY-MM-DD): 2005-01-13
Title of Journal: Journal of Medicinal Chemistry
Volume: 48
Issue / Number: 1
Start Page: 163
End Page: 170
Document Type: Article
ID: 217857.0
Structural basis for the regulation of insulin-like growth factors by IGF binding proteins
Authors: Siwanowicz, I.; Popowicz, G. M.; Wisniewska, M.; Huber, R.; Kuenkele, K. P.; Lang, K.; Engh, R. A.; Holak, T. A.
Date of Publication (YYYY-MM-DD): 2005-01
Title of Journal: Structure
Volume: 13
Issue / Number: 1
Start Page: 155
End Page: 167
Document Type: Article
ID: 221991.0
The typically disordered n-terminus of PKA can fold as a helix and project the myristoylation site into solution
Authors: Breitenlechner, C.; Engh, R. A.; Huber, R.; Kinzel, V.; Bossemeyer, D.; Gassel, M.
Date of Publication (YYYY-MM-DD): 2004-06-22
Title of Journal: Biochemistry
Volume: 43
Issue / Number: 24
Start Page: 7743
End Page: 7749
Document Type: Article
ID: 222095.0
The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A
Authors: Gassel, M.; Breitenlechner, C. B.; Konig, N.; Huber, R.; Engh, R. A.; Bossemeyer, D.
Date of Publication (YYYY-MM-DD): 2004-05-28
Title of Journal: Journal of Biological Chemistry
Volume: 279
Issue / Number: 22
Start Page: 23679
End Page: 23690
Document Type: Article
ID: 222081.0
Structure-based optimization of novel azepane derivatives as PKB inhibitors
Authors: Breitenlechner, C. B.; Wegge, T.; Berillon, L.; Graul, K.; Marzenell, M.; Friebe, W. G.; Thomas, U.; Schumacher, R.; Huber, R.; Engh, R. A.; Masjost, B.
Date of Publication (YYYY-MM-DD): 2004-03-11
Title of Journal: Journal of Medicinal Chemistry
Volume: 47
Issue / Number: 6
Start Page: 1375
End Page: 1390
Document Type: Article
ID: 121672.0
In vitro folding and characterization of the p53 DNA binding domain
Authors: Klein, C.; Hesse, F.; Dehner, A.; Engh, R. A.; Schwaiger, M.; Hansen, S.
Date of Publication (YYYY-MM-DD): 2004-01
Title of Journal: Biological Chemistry
Volume: 385
Issue / Number: 1
Start Page: 95
End Page: 102
Document Type: Article
ID: 119849.0
Entries: 1-10  
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