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Entries: 1-10  
Noncompaction of the Ventricular Myocardium Is Associated with a De Novo Mutation in the beta-Myosin Heavy Chain Gene
Authors: Budde, B. S.; Binner, P.; Waldmuller, S.; Hohne, W.; Blankenfeldt, W.; Hassfeld, S.; Bromsen, J.; Dermintzoglou, A.; Wieczorek, M.; May, E.; Kirst, E.; Selignow, C.; Rackebrandt, K.; Muller, M.; Goody, R. S.; Vosberg, H. P.; Nurnberg, P.; Scheffold, T.
Date of Publication (YYYY-MM-DD): 2007
Volume: 2
Issue / Number: 12
Start Page: e1362
Document Type: Article
ID: 354765.0
Expressing engineered thymidylate kinase variants in human cells to improve AZT phosphorylation and human immunodeficiency virus inhibition
Authors: Woehrl, B. M.; Loubiere, L.; Brundiers, R.; Goody, R. S.; Klatzmann, D.; Konrad, M.
Date of Publication (YYYY-MM-DD): 2005-03
Title of Journal: Journal of General Virology
Volume: 86
Start Page: 757
End Page: 764
Document Type: Article
ID: 256371.0
Multiparameter single-molecule fluorescence spectroscopy reveals heterogeneity of HIV-1 reverse transcriptase: primer/template complexes
Authors: Rothwell, P. J.; Berger, S.; Kensch, O.; Felekyan, S.; Antonik, M.; Woehrl, B. M.; Restle, T.; Goody, R. S.; Seidel, C.
Date of Publication (YYYY-MM-DD): 2003-02-18
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 100
Issue / Number: 4
Start Page: 1655
End Page: 1660
Document Type: Article
ID: 124281.0
Allosteric regulation of substrate binding and product release in geranylgeranyltransferase Type II.
Authors: Thomä, N. H.; Iakovenko, A.; Kalinin, A.; Waldmann, H.; Goody, R. S.; Alexandrov, K.
Date of Publication (YYYY-MM-DD): 2001
Title of Journal: Biochemistry
Volume: 40
Start Page: 268
End Page: 274
Document Type: Article
ID: 264891.0
Potentiating AZT activation: Structure of wild-type and mutant human thymidylate kinase suggest reasons for the mutants' improved kinetics with the HIV prodrug metabolite AZTMP.
Authors: Ostermann, N.; Lavie, A.; Padiyar, S.; Brundiers, R.; Veit, T.; Reinstein, J.; Goody, R. S.; Konrad, M.; Schlichting, I.
Date of Publication (YYYY-MM-DD): 2000
Title of Journal: Journal of Molecular Biology
Volume: 304
Start Page: 43
End Page: 53
Document Type: Article
ID: 233448.0
Insights into the phosphoryltransfer mechanism of human thymidylate kinase gained from crystal structures of enzyme complexes along the reaction coordinate.
Authors: Ostermann, N.; Schlichting, I.; Brundiers, R.; Konrad, M.; Reinstein, J.; Veit, T.; Goody, R. S.; Lavie, A.
Date of Publication (YYYY-MM-DD): 2000
Title of Journal: Structure
Volume: 8
Start Page: 629
End Page: 642
Document Type: Article
ID: 233449.0
Crystal structure of the GAP domain of Gyp1p: first insights into interaction with Ypt/Rab proteins.
Authors: Rak, A.; Fedorov, R.; Alexandrov, K.; Albert, S.; Goody, R. S.; Gallwitz, D.; Scheidig, A. J.
Date of Publication (YYYY-MM-DD): 2000
Title of Journal: EMBO Journal
Volume: 19
Start Page: 5105
End Page: 5113
Document Type: Article
ID: 233712.0
Modifying human thymidylate kinase to potentiate AZT activation.
Authors: Brundiers, R.; Lavie, A.; Veit, T.; Reinstein, J.; Schlichting, I.; Ostermann, N.; Goody, R. S.; Konrad, M.
Date of Publication (YYYY-MM-DD): 1999
Title of Journal: Journal of Biological Chemistry
Volume: 274
Start Page: 35289
End Page: 35292
Document Type: Article
ID: 223405.0
Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor P1-(5′-adenosyl)P5-(5′-thymidyl) pentaphosphate (TP5A) at 2.0 Å resolution: Implications for catalysis and AZT activation.
Authors: Lavie, A.; Konrad, M.; Brundiers, R.; Goody, R. S.; Schlichting, I.; Reinstein, J.
Date of Publication (YYYY-MM-DD): 1998
Title of Journal: Biochemistry
Volume: 37
Start Page: 3677
End Page: 3686
Document Type: Article
ID: 228769.0
Structural basis for efficient phosphorylation of 3′-azidothymidine monophosphate by Escherichia coli thymidylate kinase.
Authors: Lavie, A.; Ostermann, N.; Brundiers, R.; Goody, R. S.; Reinstein, J.; Konrad, M.; Schlichting, I.
Date of Publication (YYYY-MM-DD): 1998
Title of Journal: Proceedings of the National Academy of Sciences USA
Volume: 95
Start Page: 14045
End Page: 14050
Document Type: Article
ID: 228771.0
Entries: 1-10  
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